SCHEMBL8149482

SCHEMBL8149482

O=C(c1ccc(O)cc1)C(O)c1ccc(O)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.60
CES1 P23141 3/20 0.60
LMNA P02545 4/20 0.59
ALDH1A1 P00352 2/20 0.50
PDPK1 O15530 1/20 0.50
KDM4E B2RXH2 1/20 0.50
HSD17B10 Q99714 2/20 0.49
TSHR P16473 1/20 0.49
ESR1 P03372 2/20 0.48
MAPT P10636 2/20 0.48
ESR2 Q92731 1/20 0.48
PKM P14618 1/20 0.48
HPGD P15428 1/20 0.48
HTT P42858 1/20 0.48
HIF1A Q16665 2/20 0.47
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
DRD1 P21728 2/20 0.46
CA12 O43570 1/20 0.46
CA3 P07451 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20576195 0.90 MAPK1 (0.57) CES2CES1LMNAALDH1A1PDPK1
SCHEMBL2544234 0.90 LMNA (0.77) CES2CES1LMNAALDH1A1PDPK1
SCHEMBL2544232 0.90 LMNA (0.77) CES2CES1LMNAALDH1A1KDM4E
Benzoin SCHEMBL7691572 0.88 LMNA (0.81) CES2CES1LMNAALDH1A1PDPK1
SCHEMBL15483229 0.87 ENPP2 (0.52) CES2CES1LMNAALDH1A1PDPK1
SCHEMBL6473480 0.86 MAPT (0.49) CES2CES1LMNAALDH1A1KDM4E
SCHEMBL15481267 0.84 CES2 (0.46) CES2CES1LMNAALDH1A1PDPK1
Benzoin SCHEMBL5537990 0.81 LMNA (0.84) CES2CES1LMNAALDH1A1KDM4E
SCHEMBL10358631 0.81 CES2 (0.53) CES2CES1LMNAALDH1A1PDPK1
SCHEMBL10358632 0.81 CES2 (0.53) CES2CES1LMNAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6040484-A HYDROXYLATION OF PHENOLIC COMPOUNDS USING HYDROGEN PEROXIDE AND A CATALYST OF AT LEAST ONE RARE EARTH OR BISMUTH TRIFLATE; CATALYST SELECTIVITY RHODIA CHIMIE (FR) 2000-03-21 US claimed
US-5331103-A Reaction with hydrogen peroxide, hydroquinone from phenol RHONE-POULENC CHIMIE (FR) 1994-07-19 US claimed
US-4087463-A COBALT CARBONYL CATALYST MONSANTO COMPANY (US) 1978-05-02 US claimed
CN-105142622-A Sulfestrol for treating cancer CHAMAELEO PHARMA BVBA 2015-12-09 CN disclosed
US-20150283108-A1 SULFESTROL FOR TREATING CANCER CHAMAELEO PHARMA BVBA (BE) 2015-10-08 US disclosed
CN-102344350-A Preparation method for 1,2-diphenylethanone UNIV SHAANXI SCIENCE & TECH 2012-02-08 CN disclosed
US-6040484-A HYDROXYLATION OF PHENOLIC COMPOUNDS USING HYDROGEN PEROXIDE AND A CATALYST OF AT LEAST ONE RARE EARTH OR BISMUTH TRIFLATE; CATALYST SELECTIVITY RHODIA CHIMIE (FR) 2000-03-21 US disclosed
US-5331103-A Reaction with hydrogen peroxide, hydroquinone from phenol RHONE-POULENC CHIMIE (FR) 1994-07-19 US disclosed
US-5202359-A PHOTOINITIATORS THAT ARE SOLUBLE IN HIGHLY FLUORINATED MONOMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-04-13 US disclosed
EP-0057162-B1 PROCESS FOR THE PRODUCTION OF IMAGES CIBA-GEIGY AG (CH) 1984-06-27 EP disclosed
US-4368253-A Image formation process CIBA-GEIGY CORPORATION (US) 1983-01-11 US disclosed
EP-0057162-A1 Process for the production of images CIBA-GEIGY AG (CH) 1982-08-04 EP disclosed
US-4087463-A COBALT CARBONYL CATALYST MONSANTO COMPANY (US) 1978-05-02 US disclosed
US-4001216-A AMINOALKYL ETHERS OF 2,2'- AND 3,3'-DIHYDROXYDESOXYBENZOIN AMERICAN HOME PRODUCTS CORPORATION (US) 1977-01-04 US disclosed