SCHEMBL647378

SCHEMBL647378

CC(C)(C)c1ccc([I+]c2ccc(C(C)(C)C)cc2)cc1.O=S(=O)([O-])c1cccc2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NLRP3 Q96P20 1/20 0.44
HSD17B2 P37059 1/20 0.44
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
F2 P00734 3/20 0.40
PRSS1 P07477 3/20 0.40
PRSS2 P07478 3/20 0.40
PRSS3 P35030 3/20 0.40
HTR6 P50406 2/20 0.40
HSD11B1 P28845 1/20 0.40
HTR2A P28223 2/20 0.38
NR1I2 O75469 1/20 0.38
LMNA P02545 1/20 0.38
ADRA2A P08913 1/20 0.38
CYP2D6 P10635 1/20 0.38
ACHE P22303 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
KCNH2 Q12809 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2516868 0.85 CA1 (0.50) CA1CA2CA9F2PRSS1
SCHEMBL38662137 0.82 NR1I2 (0.39) NLRP3HSD17B2HSD11B1NR1I2LMNA
SCHEMBL453404 0.82 NR1I2 (0.39) NLRP3HSD17B2HSD11B1NR1I2LMNA
SCHEMBL8007140 0.81 BCL2A1 (0.37) NLRP3HSD17B2CA1CA2F2
SCHEMBL175822 0.81 HSD11B1 (0.43) HSD17B2CA1CA2HSD11B1LMNA
SCHEMBL2966140 0.79 HSD11B1 (0.43) HSD17B2CA1CA2HSD11B1ACHE
SCHEMBL6746175 0.79 HSD11B1 (0.52) NLRP3HTR6HSD11B1LMNAMEN1
SCHEMBL5684924 0.78 CA1 (0.61) CA1CA2CA9F2PRSS1
Potassium Ion SCHEMBL10962719 0.78 CA1 (0.61) CA1CA2CA9F2PRSS1
Zinc Ion SCHEMBL1683962 0.78 CA1 (0.61) CA1CA2CA9F2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220283499-A1 COMPOSITION FOR FORMING UNDERLAYER FILM, RESIST PATTERN FORMING METHOD, AND MANUFACTURING METHOD OF ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2022-09-08 US disclosed
US-11286423-B2 Laminate, manufacturing method of laminate, and image display device FUJIFILM CORPORATION (JP) 2022-03-29 US disclosed
US-20200362247-A1 LAMINATE, MANUFACTURING METHOD OF LAMINATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2020-11-19 US disclosed
US-10078265-B2 Pattern-forming method, resin, and composition JSR CORPORATION (JP) 2018-09-18 US disclosed
US-10036954-B2 2018-07-31 US disclosed
US-20180120706-A1 PATTERN FORMING METHOD, LAMINATE, AND RESIST COMPOSITION FOR ORGANIC SOLVENT DEVELOPMENT FUJIFILM CORPORATION (JP) 2018-05-03 US disclosed
US-9696626-B2 Composition for forming a resist underlayer film, and pattern-forming method JSR CORPORATION (JP) 2017-07-04 US disclosed
US-9581905-B2 Composition for film formation, resist underlayer film and forming method thereof, pattern-forming method and compound JSR CORPORATION (JP) 2017-02-28 US disclosed
US-20170003595-A1 PATTERN-FORMING METHOD, RESIN, AND COMPOSITION JSR CORPORATION (JP) 2017-01-05 US disclosed
US-9447303-B2 Composition for forming resist underlayer film JSR CORPORATION (JP) 2016-09-20 US disclosed
US-20010014427-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 2001-08-16 US disclosed
US-6242161-B1 ABSORPTION COATINGS USING COPOLYMERS JSR CORPORATION (JP) 2001-06-05 US disclosed
EP-1085379-A1 Radiation-sensitive resin composition JSR Corporation (JP) 2001-03-21 EP disclosed
US-6187504-B1 PHOTOSENSITIVE BLEND CONTAINING A NAPHTHALENE SULFONIUM SULFONATE DERIVATIVE PHOTOACID GENERATOR, RESIN HAVING ALKALI INSOLUBLE GROUPS CLEAVABLE BY ACID, AN ALKALI SOLUBLE RESIN AND A SOLUBILITY CONTROL AGENT; POSITIVES, RESOLUTION JSR CORPORATION (JP) 2001-02-13 US disclosed
US-6180316-B1 SUITABLE FOR USE AS CHEMICALLY AMPLIFIED RESIST USED IN MANUFACTURING OF INTEGRATED CIRCUITS JSR CORPORATION (JP) 2001-01-30 US disclosed
EP-1048983-A1 Radiation sensitive resin composition JSR Corporation (JP) 2000-11-02 EP disclosed
EP-1045290-A2 Composition for resist underlayer film and method for producing the same JSR Corporation (JP) 2000-10-18 EP disclosed
EP-0930541-A1 Radiation sensitive resin composition JSR Corporation (JP) 1999-07-21 EP disclosed
EP-0849634-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-06-24 EP disclosed
EP-0789278-A2 Radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-08-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10078265-B2 Pattern-forming method, resin, and composition RER1, SLIRP, SRSF9 NLRP3 3464/4885HSD17B2 4006/4885CA1 898/4885
US-10036954-B2 SMURF1, DSG1, SLIRP NLRP3 4625/4885HSD17B2 3288/4885CA1 617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.