Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5637788 | 0.84 | KEAP1 (0.62) | LMNASMN1; SMN2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL7051503 | 0.84 | ALDH1A1 (0.55) | LMNASMN1; SMN2NFE2L2ALDH1A1POLB | |
| SCHEMBL18599533 | 0.80 | NR3C1 (0.50) | LMNASMN1; SMN2KEAP1NFE2L2P2RX7 | |
| SCHEMBL11672581 | 0.78 | KEAP1 (0.69) | LMNAKEAP1NFE2L2ALDH1A1POLB | |
| SCHEMBL30673310 | 0.78 | PTGS1 (0.47) | LMNAALDH1A1NR3C1 | |
| SCHEMBL26928509 | 0.78 | PTGS1 (0.47) | LMNAALDH1A1NR3C1 | |
| SCHEMBL11415903 | 0.76 | P2RX7 (0.44) | LMNASMN1; SMN2P2RX7ALDH1A1HTT | |
| SCHEMBL11973136 | 0.75 | MAPT (0.53) | LMNASMN1; SMN2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL20597533 | 0.74 | P2RX7 (0.53) | SMN1; SMN2P2RX7ALDH1A1HTT | |
| SCHEMBL1141399 | 0.74 | P2RX7 (0.53) | SMN1; SMN2P2RX7ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916350-B2 | Dye mixture of water-soluble fiber-reactive azo dyes, method for the production and use thereof | DYSTAR TEXTIFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2005-07-12 | — | — | US | disclosed |
| US-20030145396-A1 | Dye mixture of water-soluble fiber-reactive azo dyes, method for the production and use thereof | DYSTAR COLOURS DISTRIBUTION GMBH (DE) | 2003-08-07 | — | — | US | disclosed |