Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 13/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11339959 | 0.81 | SMN1; SMN2 (0.39) | NFE2L2LMNASMN1; SMN2EGFRGPBAR1 | |
| SCHEMBL6476852 | 0.80 | NOS3 (0.36) | NFE2L2LMNAKMT2A | |
| SCHEMBL7668811 | 0.77 | NFE2L2 (0.39) | NFE2L2LMNA | |
| SCHEMBL11466898 | 0.76 | EGFR (0.38) | LMNASMN1; SMN2EGFRGPBAR1 | |
| SCHEMBL5539664 | 0.74 | NFE2L2 (0.31) | NFE2L2 | |
| SCHEMBL2205464 | 0.71 | ESR1 (0.36) | LMNAMEN1KMT2A | |
| SCHEMBL306348 | 0.70 | ALDH1A1 (0.41) | NFE2L2LMNASMN1; SMN2KMT2A | |
| SCHEMBL29443546 | 0.70 | ALDH1A1 (0.41) | NFE2L2LMNASMN1; SMN2KMT2A | |
| SCHEMBL19459420 | 0.67 | SMN1; SMN2 (0.52) | LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL5537285 | 0.67 | HSP90AA1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005118520-A1 | METHOD FOR PREPARING RHODOMYCINONE DERIVATIVES | ARCHEMIS (FR) | 2005-12-15 | — | — | WO | disclosed |