Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PRKCI | P41743 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6474493 | 0.80 | NFE2L2 (0.38) | NFE2L2KMT2ALMNA | |
| SCHEMBL5539664 | 0.74 | NFE2L2 (0.31) | NFE2L2 | |
| SCHEMBL5537285 | 0.74 | HSP90AA1 (0.44) | HRH4 | |
| SCHEMBL2205464 | 0.71 | ESR1 (0.36) | CA1CA2KMT2ACA9HSD11B1 | |
| SCHEMBL306348 | 0.70 | ALDH1A1 (0.41) | NFE2L2KMT2AKDM4ELMNA | |
| SCHEMBL29443546 | 0.70 | ALDH1A1 (0.41) | NFE2L2KMT2AKDM4ELMNA | |
| SCHEMBL27726966 | 0.70 | CA2 (0.40) | NOS3NOS1NOS2NAPRTNFE2L2 | |
| SCHEMBL7668811 | 0.70 | NFE2L2 (0.39) | NFE2L2SLC40A1LMNA | |
| SCHEMBL29435567 | 0.66 | NOS3 (0.52) | NOS3NOS1NOS2NAPRTKMT2A | |
| SCHEMBL11262903 | 0.66 | NOS3 (0.52) | NOS3NOS1NOS2NAPRTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005118520-A1 | METHOD FOR PREPARING RHODOMYCINONE DERIVATIVES | ARCHEMIS (FR) | 2005-12-15 | — | — | WO | disclosed |