⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL375117 | 0.74 | CASP6 (0.41) | — | |
| SCHEMBL8765683 | 0.73 | CTSL (0.33) | — | |
| SCHEMBL2306238 | 0.72 | DPP4 (0.48) | — | |
| SCHEMBL41049 | 0.72 | — | — | |
| SCHEMBL29361780 | 0.72 | — | — | |
| SCHEMBL27892006 | 0.72 | LMNA (0.48) | — | |
| Formaldehyde SCHEMBL27551738 | 0.72 | SMN1; SMN2 (0.48) | — | |
| SCHEMBL24500155 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL16318482 | 0.70 | — | — | |
| SCHEMBL4633189 | 0.70 | DPP4 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109946454-A | A kind of Dursban monoclonal antibody and the preparation method and application thereof | 苏州快捷康生物技术有限公司 | 2019-06-28 | — | — | CN | claimed |
| US-8119563-B2 | N-substituted azacycles | FMC CORPORATION (US) | 2012-02-21 | — | — | US | claimed |
| US-20100234343-A1 | INHIBITORS OF ION CHANNELS | ICAGEN, INC. (US) | 2010-09-16 | — | — | US | claimed |
| US-7705158-B2 | Inhibitors of ion channels | ICAGEN, INC. (US) | 2010-04-27 | — | — | US | claimed |
| US-20090215821-A1 | N-Substituted Azacycles | FMC CORPORATION | 2009-08-27 | — | — | US | claimed |
| EP-1673083-A4 | N-SUBSTITUTED AZACYCLES | BAYER CROPSCIENCE AG (DE) | 2008-12-17 | — | — | EP | claimed |
| EP-1673083-A2 | N-SUBSTITUTED AZACYCLES | FMC CORPORATION (US) | 2006-06-28 | — | — | EP | claimed |
| WO-2005036961-A2 | N-SUBSTITUTED AZACYCLES | FMC CORPORATION (US) | 2005-04-28 | — | — | WO | claimed |
| EP-0354297-B1 | THIADIAZINES, PROCESS FOR PRODUCTION THEREOF, AND INSECTICIDAL AND ACARICIDAL AGENTS COMPRISING THE THIADIAZINES | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-08-05 | — | — | EP | claimed |
| EP-0112524-B1 | TRICHLOROACRYLOYL OXIME DERIVATIVES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-05-28 | — | — | EP | claimed |
| US-4581365-A | Trichloroacryloyl oxime fungicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-04-08 | — | — | US | claimed |
| EP-0112524-A1 | Trichloroacryloyl oxime derivatives | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1984-07-04 | — | — | EP | claimed |
| WO-2020028221-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2020-02-06 | — | — | WO | disclosed |
| US-20190322676-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARM INC (US) | 2019-10-24 | — | — | US | disclosed |
| WO-2018118838-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2018-06-28 | — | — | WO | disclosed |
| US-8338608-B2 | Inhibitors of ion channels | ICAGEN INC. (US) | 2012-12-25 | — | — | US | disclosed |
| EP-0255778-A1 | Thermoplastic aromatic polyether-pyridines and process for preparing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1988-02-10 | — | — | EP | disclosed |
| EP-0112524-B1 | TRICHLOROACRYLOYL OXIME DERIVATIVES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-05-28 | — | — | EP | disclosed |
| US-4581365-A | Trichloroacryloyl oxime fungicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-04-08 | — | — | US | disclosed |
| EP-0112524-A1 | Trichloroacryloyl oxime derivatives | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1984-07-04 | — | — | EP | disclosed |