SCHEMBL8765683

SCHEMBL8765683

[O]c1ncccc1C(Cl)(Cl)Cl

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSL P07711 1/20 0.33
PTPRC P08575 1/20 0.33
CTSS P25774 1/20 0.33
PTPN13 Q12923 1/20 0.33
GAA P10253 2/20 0.33
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 3/20 0.32
LMNA P02545 2/20 0.32
TDP1 Q9NUW8 4/20 0.32
PLCG1 P19174 2/20 0.32
TDP2 O95551 1/20 0.32
NSD2 O96028 1/20 0.32
ABL1 P00519 1/20 0.32
CES1 P23141 1/20 0.32
PAX8 Q06710 1/20 0.32
RIN1 Q13671 1/20 0.32
MEN1 O00255 1/20 0.32
THRB P10828 1/20 0.32
BLM P54132 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1494212 0.77 CA2 (0.39) CTSLPTPRCCTSSPTPN13ALDH1A1
SCHEMBL2305693 0.77 EPHX2 (0.43) GAAPAX8MEN1KMT2ANFE2L2
SCHEMBL30046969 0.74 SMN1; SMN2 (0.42) GAAALDH1A1SMN1; SMN2LMNATDP1
SCHEMBL10354989 0.74 KDM4E (0.32) GAAALDH1A1SMN1; SMN2LMNATDP1
SCHEMBL4764441 0.74 SMN1; SMN2 (0.42) GAAALDH1A1SMN1; SMN2LMNATDP1
SCHEMBL647471 0.73
SCHEMBL8977118 0.73 L3MBTL1 (0.37) ALDH1A1SMN1; SMN2LMNATDP1CYP3A4
SCHEMBL8765692 0.73 ALDH1A1 (0.34) GAAALDH1A1SMN1; SMN2LMNATDP1
SCHEMBL10726947 0.73 NOS3 (0.46) GAAALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL8778858 0.73 TRIM24 (0.42) ALDH1A1SMN1; SMN2LMNATDP1CDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0778267-A1 SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1997-06-11 EP disclosed