Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13427773 | 0.91 | GAA (0.50) | NPSR1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL6399107 | 0.84 | CA1 (0.50) | CES2CES1RAB9ANPSR1MEN1 | |
| SCHEMBL6444093 | 0.84 | CES2 (0.47) | CES2CES1RAB9ANPSR1MEN1 | |
| SCHEMBL14648180 | 0.83 | MAPT (0.53) | CES2CES1RAB9ANPSR1MEN1 | |
| SCHEMBL10764332 | 0.82 | CES2 (0.45) | CES2CES1RAB9ANPSR1MEN1 | |
| SCHEMBL30585518 | 0.82 | RAB9A (0.49) | CES2CES1RAB9ANPSR1MEN1 | |
| SCHEMBL4709268 | 0.79 | MAPK1 (0.52) | RAB9ANPSR1MEN1KMT2ACA1 | |
| SCHEMBL23482921 | 0.79 | LMNA (0.48) | CES2CES1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL51763 | 0.79 | ESR1 (0.52) | MEN1KMT2ACA1CA2MAPT | |
| SCHEMBL9123149 | 0.78 | ALOX5 (0.53) | RAB9AMEN1KMT2AACACBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867297-B1 | Process for synthesizing 4-substituted azetidinone derivatives | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2005-03-15 | — | — | US | disclosed |
| EP-0638552-B1 | PROCESS FOR SYNTHESIZING 4-SUBSTITUTED AZETIDINONE DERIVATIVE | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2003-06-04 | — | — | EP | disclosed |
| EP-0638552-A1 | PROCESS FOR SYNTHESIZING 4-SUBSTITUTED AZETIDINONE DERIVATIVE | SUNTORY LIMITED (JP) | 1995-02-15 | — | — | EP | disclosed |