Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | MMP16 | P51512 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2108847 | 0.82 | KCNK3 (0.49) | PTGS2PTGS1ELANEMMP1MMP2 | |
| SCHEMBL6472728 | 0.78 | PTGS2 (0.51) | PTGS2PTGS1MMP1MMP2MMP9 | |
| SCHEMBL27777280 | 0.76 | HDAC4 (0.53) | ACLY | |
| SCHEMBL2541518 | 0.74 | PTGS2 (0.62) | PTGS2PTGS1MMP1MMP2MMP9 | |
| SCHEMBL6272901 | 0.74 | PTGS2 (0.52) | PTGS2PTGS1MMP12MMP13CYP2C19 | |
| SCHEMBL1957918 | 0.73 | PTGS2 (0.56) | PTGS2PTGS1MMP1MMP2MMP9 | |
| SCHEMBL2724112 | 0.73 | PTGS2 (0.56) | PTGS2PTGS1MMP1MMP2MMP9 | |
| SCHEMBL4026660 | 0.72 | ACMSD (0.55) | KCNK3KCNK9ACLYAKR1C3AKR1C2 | |
| SCHEMBL28768954 | 0.72 | GSTA1 (0.45) | ACLYAKR1C2AKR1C1 | |
| SCHEMBL27332946 | 0.71 | PTGS2 (0.58) | PTGS2PTGS1MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005110963-A1 | (BIPHENYL-3-YL)-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF AND THEIR USE IN THERAPY | CELLZOME AG (DE) | 2005-11-24 | — | — | WO | disclosed |