SCHEMBL647518

SCHEMBL647518

Brc1cccc(-c2ccccn2)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 2/20 0.64
DCTPP1 Q9H773 1/20 0.52
LMNA P02545 3/20 0.50
KDM4E B2RXH2 2/20 0.50
CCR1 P32246 2/20 0.50
CCR5 P51681 2/20 0.50
CCR8 P51685 2/20 0.50
CYP1A2 P05177 1/20 0.50
POLB P06746 1/20 0.50
METAP1 P53582 1/20 0.50
BLM P54132 1/20 0.50
HIF1A Q16665 1/20 0.50
DOHH Q9BU89 1/20 0.50
P4HTM Q9NXG6 1/20 0.50
CYP2A6 P11509 1/20 0.50
IDO1 P14902 2/20 0.49
METAP2 P50579 1/20 0.49
TP53 P04637 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
ALPL P05186 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL751847 0.98 GRM5 (0.62) GRM5DCTPP1LMNAKDM4ECCR1
SCHEMBL752286 0.98 GRM5 (0.62) GRM5DCTPP1LMNAKDM4ECCR1
SCHEMBL28007675 0.98 GRM5 (0.62) GRM5DCTPP1LMNAKDM4ECCR1
SCHEMBL26498985 0.96 GRM5 (0.60) GRM5DCTPP1LMNAKDM4ECCR1
SCHEMBL14595514 0.96 GRM5 (0.60) GRM5DCTPP1LMNAKDM4ECCR1
SCHEMBL28007678 0.96 GRM5 (0.60) GRM5DCTPP1LMNAKDM4ECCR1
SCHEMBL29412559 0.96 GRM5 (0.60) GRM5DCTPP1LMNAKDM4ECCR1
SCHEMBL750065 0.94 GRM5 (0.59) GRM5DCTPP1LMNAKDM4ECCR1
SCHEMBL752084 0.94 GRM5 (0.59) GRM5DCTPP1LMNAKDM4ECCR1
SCHEMBL752402 0.94 GRM5 (0.59) GRM5DCTPP1LMNAKDM4ECCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 531 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112940045-A Bivalent platinum complex, preparation method thereof and application thereof in luminescent material 南京工业大学 2021-06-11 CN claimed
US-9312503-B2 Green light iridium (III) complex and a method of preparing the same SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD (CN) 2016-04-12 US claimed
US-20150357585-A1 A GREEN LIGHT IRIDIUM (III) COMPLEX AND A METHOD OF PREPARING THE SAME Shenzhen China Star Optoelectronics Technology Co. Ltd. (CN) 2015-12-10 US claimed
US-20260085048-A1 ACSS2 INHIBITORS AND METHODS OF USE THEREOF EPIVARIO INC (US) 2026-03-26 US disclosed
US-12503644-B2 Metal assisted delayed fluorescent emitters for organic light-emitting diodes ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2025-12-23 US disclosed
US-12441689-B2 ACSS2 inhibitors and methods of use thereof EPIVARIO, INC. (US) 2025-10-14 US disclosed
EP-4618755-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2025-09-24 EP disclosed
EP-4349814-B1 IRIDIUM COMPLEX COMPOUND, COMPOSITION CONTAINING IRIDIUM COMPLEX COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR PRODUCING SAME MITSUBISHI CHEM CORP (JP) 2025-07-09 EP disclosed
CN-113683625-B Metal-assisted delayed fluorescence emitters for organic light emitting diodes 亚利桑那州立大学董事会 2025-06-10 CN disclosed
CN-119930686-A Cuprous halide complex high-entropy luminescent material and preparation method and application thereof 厦门大学 2025-05-06 CN disclosed
US-12275747-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2025-04-15 US disclosed
CN-1512999-A 2-{[N-(2-amino-3-(heteroaryl or aryl) propionyl)-aminoacyl]-amino}- alkylboronic acid derivatives ��˹��ŵ�� 2004-07-14 CN disclosed
WO-2004050895-A2 METHODS AND COMPOSITIONS FOR INDUCING APOPTOSIS IN CANCER CELLS IRM LLC (BM) 2004-06-17 WO disclosed
EP-1399468-A1 2-((N-(2-AMINO-3-(HETEROARYL OR ARYL)PROPIONYL)-AMINOACYL)-AMINO)-ALKYLBORONIC ACID DERIVATIVES Novartis AG (CH) 2004-03-24 EP disclosed
EP-1366113-A1 METAL-CONTAINING DENDRIMERS ISIS INNOVATION LIMITED (GB) 2003-12-03 EP disclosed
WO-2003079736-A1 PHOSPHORESCENT DENDRIMERS FOR USE IN LIGHT-EMITTING DEVICES ISIS INNOVATION LIMITED (GB) 2003-09-25 WO disclosed
US-20020193532-A1 Comprises polystyrene and organometallic polymer; luminescence; for use in spin coating and ink jet printing SUMITOMO CHEMICAL COMPANY, LIMITED 2002-12-19 US disclosed
WO-2002096933-A1 2-{[N-(2-AMINO-3-(HETEROARYL OR ARYL)PROPIONYL)-AMINOACYL]-AMINO}-ALKYLBORONIC ACID DERIVATIVES NOVARTIS AG (CH) 2002-12-05 WO disclosed
EP-1245659-A1 Polymeric light emitting substance and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-10-02 EP disclosed
WO-2002066552-A1 METAL-CONTAINING DENDRIMERS ISIS INNOVATION LIMITED (GB) 2002-08-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12503644-B2 Metal assisted delayed fluorescent emitters for organic light-emitting diodes ETFA, CACNA1F, CYP4F2 GRM5 1567/4885DCTPP1 2480/4885LMNA 3125/4885
US-20150357585-A1 A GREEN LIGHT IRIDIUM (III) COMPLEX AND A METHOD OF PREPARING THE SAME ALG3, RTN3, GPR3 GRM5 305/4885DCTPP1 4429/4885LMNA 4357/4885
US-20260085048-A1 ACSS2 INHIBITORS AND METHODS OF USE THEREOF ACSS2, GLS2, ACSL3 GRM5 408/4885DCTPP1 3821/4885LMNA 2111/4885
US-12275747-B2 Organic electroluminescent materials and devices ODC1, OCIAD1, OCIAD2 GRM5 2613/4885DCTPP1 2518/4885LMNA 1937/4885
US-12441689-B2 ACSS2 inhibitors and methods of use thereof ACSS2, ADSS2, GLS2 GRM5 950/4885DCTPP1 2915/4885LMNA 3750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.