Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 17/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.35 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.35 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.35 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.35 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.35 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.35 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.35 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.35 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.35 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.35 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.35 |
| ▸ | PSMA6 | P60900 | 1/20 | 0.35 |
| ▸ | PSMA8 | Q8TAA3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6487933 | 0.92 | CTSS (0.38) | CTSSPKMSMN1; SMN2 | |
| SCHEMBL6484807 | 0.89 | CTSS (0.45) | CTSSCAPN1PKMSMN1; SMN2 | |
| SCHEMBL6482897 | 0.88 | CTSS (0.45) | CTSSCAPN1PSMB11PSMA7PSMB1 | |
| SCHEMBL6591010 | 0.87 | CTSL (0.32) | CTSS | |
| SCHEMBL6477041 | 0.86 | CTSS (0.47) | CTSSPKMSMN1; SMN2 | |
| SCHEMBL6476643 | 0.86 | CTSS (0.39) | CTSSPKMSMN1; SMN2 | |
| SCHEMBL6475532 | 0.85 | CTSS (0.41) | CTSSCAPN1PKMSMN1; SMN2 | |
| SCHEMBL6474920 | 0.84 | CTSS (0.41) | CTSSCAPN1 | |
| SCHEMBL6476747 | 0.84 | CTSS (0.45) | CTSSCAPN1PKMSMN1; SMN2 | |
| SCHEMBL6476369 | 0.81 | CTSS (0.43) | CTSSPSMB11PSMA7PSMB1PSMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050020588-A1 | Cysteine protease inhibitors | PEPTIMMUNE, INC. | 2005-01-27 | — | — | US | claimed |
| US-20050020588-A1 | Cysteine protease inhibitors | PEPTIMMUNE, INC. | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020588-A1 | Cysteine protease inhibitors | CTSS, CTSE, CTSV | CTSS 1/4885CAPN1 62/4885PSMB11 316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.