Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 5/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5108679 | 0.80 | HTR2A (0.46) | ALDH1A1HTR2ASLC6A4KCNH2GAA | |
| SCHEMBL6739761 | 0.80 | MEN1 (0.41) | CASP1ALDH1A1ALOX5GAATDP1 | |
| SCHEMBL5682803 | 0.80 | PDE10A (0.45) | CYP2D6CASP1ALDH1A1ALOX5GAA | |
| SCHEMBL6476804 | 0.79 | CASP1 (0.33) | CASP1ALDH1A1ALOX5TDP1CYP3A4 | |
| SCHEMBL6742125 | 0.79 | CASP1 (0.38) | CASP1ALDH1A1ALOX5GAATDP1 | |
| SCHEMBL28252731 | 0.78 | CASP1 (0.42) | CASP1ALDH1A1GAATDP1CYP3A4 | |
| SCHEMBL29433029 | 0.78 | CASP1 (0.42) | CASP1ALDH1A1GAATDP1CYP3A4 | |
| SCHEMBL33893 | 0.78 | CASP1 (0.42) | CASP1ALDH1A1GAATDP1CYP3A4 | |
| SCHEMBL6483746 | 0.77 | MEN1 (0.47) | ALDH1A1GAATDP1CYP3A4ALOX15 | |
| SCHEMBL6740875 | 0.77 | MEN1 (0.36) | CASP1ALDH1A1GAATDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1239467-C | Primary intermediates for oxidative dyeing of hair | P & G CLAIROL INC (US) | 2006-02-01 | — | — | CN | disclosed |
| US-6951574-B2 | Primary intermediates for oxidative coloration of hair | THE PROCTER & GAMBLE COMPANY (US) | 2005-10-04 | — | — | US | disclosed |
| US-20040255403-A1 | Primary intermediates for oxidative coloration of hair | LIM MU-ILL (US) | 2004-12-23 | — | — | US | disclosed |
| US-6780999-B2 | Primary intermediates for oxidative coloration of hair | THE PROCTER & GAMBLE COMPANY | 2004-08-24 | — | — | US | disclosed |
| CN-1486297-A | Primary intermediates for oxidative dyeing of hair | P&G | 2004-03-31 | — | — | CN | disclosed |
| EP-1353895-A2 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-Clairol, Inc. (US) | 2003-10-22 | — | — | EP | disclosed |
| US-20020144357-A1 | Primary intermediates for oxidative coloration of hair | WELLA OPERATIONS US, LLC | 2002-10-10 | — | — | US | disclosed |
| WO-2002058632-A2 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-CLARIOL, INC. (US) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040255403-A1 | Primary intermediates for oxidative coloration of hair | COX5A, CYC1, MT-CO1 | CYP2D6 303/4885CASP1 651/4885ALDH1A1 7/4885 |
| US-20020144357-A1 | Primary intermediates for oxidative coloration of hair | COX5A, CYC1, MT-CO1 | CYP2D6 303/4885CASP1 651/4885ALDH1A1 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.