Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11674658 | 0.80 | MEN1 (0.43) | MEN1KMT2AHTTMAPK1MAPT | |
| SCHEMBL6477831 | 0.80 | CYP2D6 (0.38) | ALOX5MEN1KMT2AHTTMAPK1 | |
| SCHEMBL2739345 | 0.79 | PDE10A (0.52) | PDE10AALOX5MEN1KMT2AHTT | |
| SCHEMBL17774759 | 0.78 | PDE10A (0.50) | PDE10AALOX5MEN1KMT2AHTT | |
| SCHEMBL3194749 | 0.78 | PDE10A (0.50) | PDE10AALOX5MEN1KMT2AHTT | |
| SCHEMBL17774755 | 0.78 | PDE10A (0.50) | PDE10AALOX5MEN1KMT2AHTT | |
| SCHEMBL5681804 | 0.78 | PDE10A (0.50) | PDE10AALOX5MEN1KMT2AHTT | |
| SCHEMBL4625449 | 0.78 | ALOX5 (0.40) | PDE10AALOX5MEN1KMT2AHTT | |
| SCHEMBL5682687 | 0.78 | KMT2A (0.68) | PDE10AALOX5MEN1KMT2AHTT | |
| SCHEMBL17774742 | 0.77 | PDE10A (0.41) | PDE10AALOX5MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1359891-B1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P & G CLAIROL INC (US) | 2006-03-15 | — | — | EP | disclosed |
| US-6838561-B2 | Primary intermediates for oxidative coloration of hair | THE PROCTER & GAMBLE COMPANY (US) | 2005-01-04 | — | — | US | disclosed |
| EP-1359891-A4 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P & G CLAIROL INC (US) | 2004-12-01 | — | — | EP | disclosed |
| CN-1487817-A | Primary intermediates for oxidative dyeing of hair | P&G | 2004-04-07 | — | — | CN | disclosed |
| EP-1359891-A2 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-Clairol, Inc. (US) | 2003-11-12 | — | — | EP | disclosed |
| US-20020144358-A1 | Primary intermediates for oxidative coloration of hair | WELLA OPERATIONS US, LLC | 2002-10-10 | — | — | US | disclosed |
| WO-2002062308-A2 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-CLAIROL, INC. (US) | 2002-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020144358-A1 | Primary intermediates for oxidative coloration of hair | COX5A, CYC1, MT-CO1 | PDE10A 2217/4885ALOX5 561/4885MEN1 3545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.