Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 4/20 | 0.35 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.35 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 5/20 | 0.34 |
| ▸ | IDH1 | O75874 | 7/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6478251 | 0.92 | LIPE (0.37) | GCGRKCNN3TEAD1METAP2LIPE | |
| SCHEMBL4849155 | 0.92 | SMPD3 (0.38) | GCGRKCNN3TEAD1METAP2LIPE | |
| SCHEMBL4845087 | 0.91 | GCGR (0.36) | GCGRLIPEIDH1 | |
| SCHEMBL4848881 | 0.90 | GCGR (0.38) | GCGRLIPEIDH1 | |
| SCHEMBL6479033 | 0.90 | LIPE (0.33) | GCGRKCNN3TEAD1METAP2LIPE | |
| SCHEMBL6478244 | 0.89 | KCNN3 (0.34) | GCGRKCNN3TEAD1METAP2LIPE | |
| SCHEMBL4845094 | 0.88 | LIPE (0.36) | GCGRLIPEIDH1EPHX2 | |
| SCHEMBL4850936 | 0.88 | F2R (0.43) | GCGRKCNN3LIPEIDH1EPHX2 | |
| SCHEMBL6478087 | 0.88 | GCGR (0.36) | GCGRKCNN3LIPEIDH1EPHX2 | |
| SCHEMBL6488797 | 0.86 | CCR2 (0.36) | GCGRMETAP2LIPEIDH1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897225-B1 | Inhibitors of αLβ2 mediated cell adhesion | TANABE SEIYAKU CO., LTD. (JP) | 2005-05-24 | — | — | US | disclosed |