Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | PSEN1 | P49768 | 6/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 6/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 6/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 6/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 6/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | WDR5 | P61964 | 2/20 | 0.39 |
| ▸ | BRS3 | P32247 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.39 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.39 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.39 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.39 |
| ▸ | ATP4A | P20648 | 2/20 | 0.39 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.39 |
| ▸ | ATP4B | P51164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5360268 | 0.93 | CYP2C9 (0.49) | CYP2C9PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5370500 | 0.85 | CYP2C9 (0.49) | CYP2C9KMT2AALDH1A1WDR5BRS3 | |
| SCHEMBL5367365 | 0.84 | CYP2C9 (0.42) | CYP2C9PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5332714 | 0.83 | CYP2C9 (0.42) | CYP2C9PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5332710 | 0.83 | CYP2C9 (0.42) | CYP2C9PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5763595 | 0.83 | CYP2C9 (0.42) | CYP2C9PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7841398 | 0.80 | CYP2C9 (0.41) | CYP2C9KMT2AALDH1A1WDR5BRS3 | |
| SCHEMBL7016039 | 0.79 | CYP2C9 (0.51) | CYP2C9PSEN1PSEN2APH1BNCSTN | |
| Agn-201904 SCHEMBL5764638 | 0.78 | CYP2C9 (0.40) | CYP2C9PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5760796 | 0.78 | CYP2C9 (0.42) | CYP2C9PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897227-B2 | Prodrugs of proton pump inhibitors | Winston Pharmaceuticals, Inc. (US) | 2005-05-24 | — | — | US | disclosed |
| US-20040102484-A1 | Prodrugs of proton pump inhibitors | ALEVIUM PHARMACEUTICALS, INC. | 2004-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102484-A1 | Prodrugs of proton pump inhibitors | ABCB11, SLC10A2, SI | CYP2C9 92/4885PSEN1 2674/4885PSEN2 3583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.