Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.36 |
| ▸ | LIPE | Q05469 | 11/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6488797 | 0.89 | CCR2 (0.36) | PAX8LIPENR1H2NR1H3GCGR | |
| SCHEMBL4849155 | 0.88 | SMPD3 (0.38) | DDR1LIPEKCNN3GCGR | |
| SCHEMBL14254709 | 0.86 | GRM2 (0.37) | LIPEKCNN3 | |
| SCHEMBL6477360 | 0.86 | GCGR (0.35) | LIPEKCNN3GCGR | |
| SCHEMBL6478091 | 0.86 | KCNN3 (0.35) | PAX8LIPEKCNN3GCGR | |
| SCHEMBL4845087 | 0.85 | GCGR (0.36) | LIPEGCGR | |
| SCHEMBL6478251 | 0.85 | LIPE (0.37) | LIPEKCNN3GCGR | |
| SCHEMBL4848707 | 0.85 | KCNN3 (0.36) | LIPEKCNH2KCNN3GCGR | |
| SCHEMBL4847817 | 0.85 | KCNN3 (0.38) | LIPEKCNN3GCGR | |
| SCHEMBL14254710 | 0.85 | KCNN3 (0.36) | LIPEKCNH2KCNN3GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897225-B1 | Inhibitors of αLβ2 mediated cell adhesion | TANABE SEIYAKU CO., LTD. (JP) | 2005-05-24 | — | — | US | disclosed |