SCHEMBL401165

SCHEMBL401165

Clc1ccc(C(=C2C=CC=C2)c2ccc(Cl)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.46
CES1 P23141 3/20 0.46
CYP3A4 P08684 4/20 0.44
MAPK1 P28482 4/20 0.44
TSHR P16473 3/20 0.44
ALOX15 P16050 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
ATM Q13315 1/20 0.44
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
LMNA P02545 3/20 0.42
CYP2A6 P11509 1/20 0.42
HPGD P15428 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
MAPT P10636 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
KDM4E B2RXH2 2/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
MITF O75030 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11327650 0.91 CES2 (0.54) CES2CES1CYP3A4MAPK1TSHR
SCHEMBL23341534 0.89 CES2 (0.55) CES2CES1CYP3A4TSHRL3MBTL1
SCHEMBL8916255 0.81 PTGS2 (0.55)
SCHEMBL29712521 0.77 CES2 (0.44) CES2CES1CYP3A4MAPK1TSHR
SCHEMBL17995167 0.77 CES2 (0.44) CES2CES1CYP3A4MAPK1TSHR
SCHEMBL29712522 0.77 CES2 (0.44) CES2CES1CYP3A4MAPK1TSHR
SCHEMBL2873871 0.77 ALDH1A1 (0.44) CES2CES1CYP3A4MAPK1TSHR
SCHEMBL647841 0.76 TDP1 (0.40) CES2CES1CYP3A4MAPK1TSHR
SCHEMBL11318752 0.75 CES2 (0.42) CES2CES1CYP3A4MAPK1TSHR
SCHEMBL11327194 0.75 HDAC3 (0.41) CES2CES1CYP3A4MAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10745538-B2 Thermoplastic polymer compositions MILLIKEN & COMPANY (US) 2020-08-18 US disclosed
US-20190233614-A1 THERMOPLASTIC POLYMER COMPOSITIONS MILLIKEN & COMPANY 2019-08-01 US disclosed
US-10273346-B2 Thermoplastic polymer compositions MILLIKEN & COMPANY (US) 2019-04-30 US disclosed
EP-2275457-B1 Propylene-based polymer composition, and molded products, sheets, films, laminates and non-woven fabrics obtained therefrom MITSUI CHEMICALS INC (JP) 2016-11-23 EP disclosed
EP-2275451-B1 Method for producing propylene-based copolymer MITSUI CHEMICALS INC (JP) 2016-10-19 EP disclosed
US-20160280819-A1 CATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING OLEFIN POLYMER, METHOD FOR PRODUCING PROPYLENE-BASED COPOLYMER, PROPYLENE POLYMER, PROPYLENE-BASED POLYMER COMPOSITION, AND USE OF THOSE MITSUI CHEMICALS, INC. (JP) 2016-09-29 US disclosed
US-20160229986-A1 THERMOPLASTIC POLYMER COMPOSITIONS MILLIKEN & COMPANY 2016-08-11 US disclosed
US-20160229986-A1 THERMOPLASTIC POLYMER COMPOSITIONS MILLIKEN & COMPANY 2016-08-11 US disclosed
EP-1900758-B9 METHOD FOR PRODUCING OLEFIN POLYMER MITSUI CHEMICALS INC (JP) 2016-07-13 EP disclosed
US-9382356-B2 Catalyst for olefin polymerization, method for producing olefin polymer, method for producing propylene-based copolymer, propylene polymer, propylene-based polymer composition, and use of those MITSUI CHEMICALS, INC. (JP) 2016-07-05 US disclosed
EP-1900758-B1 METHOD FOR PRODUCING OLEFIN POLYMER MITSUI CHEMICALS INC (JP) 2016-03-16 EP disclosed
US-8101684-B2 Thermoplastic resin composition for sealing solar cell, sheet for sealing solar cell and solar cell MITSUI CHEMICALS, INC. (JP) 2012-01-24 US disclosed
EP-2275451-A2 Method for producing propylene-based copolymer Mitsui Chemicals, Inc. (JP) 2011-01-19 EP disclosed
EP-2275457-A2 Propylene polymer, propylene-based polymer composition, and use of these Mitsui Chemicals, Inc. (JP) 2011-01-19 EP disclosed
US-20100000600-A1 THERMOPLASTIC RESIN COMPOSITION FOR SEALING SOLAR CELL, SHEET FOR SEALING SOLAR CELL AND SOLAR CELL MITSUI CHEMICALS, INC. 2010-01-07 US disclosed
EP-2085420-A1 POLYPROPYLENE RESIN FILM AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2009-08-05 EP disclosed
EP-2048194-A1 THERMOPLASTIC RESIN COMPOSITION FOR SOLAR CELL SEALING, SHEET FOR SOLAR CELL SEALING, AND SOLAR CELL Mitsui Chemicals, Inc. (JP) 2009-04-15 EP disclosed
US-20080220193-A1 Catalyst for olefin polymerization, method for producing olefin polymer, method for producing propylene-based copolymer, propylene polymer, propylene-based polymer composition, and use of those MITSUI CHEMICALS, INC. 2008-09-11 US disclosed
EP-1900758-A1 CATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING OLEFIN POLYMER, METHOD FOR PRODUCING PROPYLENE COPOLYMER, PROPYLENE POLYMER, PROPYLENE POLYMER COMPOSITION, AND USE OF THOSE Mitsui Chemicals, Inc. (JP) 2008-03-19 EP disclosed