Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | CPN1 | P15169 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6531412 | 0.80 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2AEPHX1 | |
| SCHEMBL6533465 | 0.79 | TMEM97 (0.45) | ALDH1A1MEN1KMT2A | |
| SCHEMBL6531544 | 0.73 | TMEM97 (0.43) | — | |
| SCHEMBL6531126 | 0.73 | TMEM97 (0.50) | ALDH1A1 | |
| SCHEMBL6479225 | 0.72 | PRMT5 (0.41) | CYP2C19ALDH1A1MEN1KMT2A | |
| SCHEMBL7764841 | 0.71 | EPHX1 (0.52) | CYP2C9CYP2C19HIF1AMEN1KMT2A | |
| SCHEMBL6533444 | 0.70 | TMEM97 (0.55) | ALDH1A1 | |
| SCHEMBL30771271 | 0.70 | EPHX1 (0.50) | CYP2C9CYP2C19HIF1AALDH1A1MEN1 | |
| SCHEMBL3258681 | 0.68 | CPA1 (0.36) | MEN1KMT2A | |
| SCHEMBL7509023 | 0.68 | CYP2C9 (0.40) | CYP2C9CYP2C19HIF1ABCHECPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572627-A1 | DRUGS FOR CHRONIC PAIN | Nicox S.A. (FR) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004054965-A1 | DRUGS FOR CHRONIC PAIN | NICOX S.A. (FR) | 2004-07-01 | — | — | WO | disclosed |