Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.60 |
| ▸ | IL1RN | P18510 | 1/20 | 0.60 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PGR | P06401 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2444333 | 0.81 | KEAP1 (0.64) | KEAP1IL1RNERAP1ALDH1A1PKM | |
| SCHEMBL3789469 | 0.81 | KEAP1 (0.64) | KEAP1IL1RNERAP1ALDH1A1PKM | |
| SCHEMBL6299262 | 0.81 | KEAP1 (0.55) | KEAP1IL1RNERAP1ALDH1A1PKM | |
| SCHEMBL29985647 | 0.80 | GAA (0.65) | KEAP1IL1RNERAP1ALDH1A1PKM | |
| SCHEMBL1151729 | 0.77 | GAA (0.80) | KEAP1IL1RNERAP1ALDH1A1PKM | |
| SCHEMBL25031372 | 0.76 | KEAP1 (1.00) | KEAP1IL1RNERAP1ALDH1A1PKM | |
| Phenyl(Phenylsulfonyl)Amine SCHEMBL114765 | 0.76 | KEAP1 (1.00) | KEAP1IL1RNERAP1ALDH1A1PKM | |
| SCHEMBL810795 | 0.76 | KMT2A (0.91) | KEAP1IL1RNERAP1ALDH1A1PKM | |
| SCHEMBL21462374 | 0.76 | PGR (0.57) | KEAP1IL1RNERAP1ALDH1A1PKM | |
| SCHEMBL2133710 | 0.76 | CES1 (0.81) | KEAP1IL1RNERAP1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050123439-A1 | Device for sensing contaminants | EASTMAN KODAK COMPANY | 2005-06-09 | — | — | US | disclosed |
| US-6395466-B1 | MIXTURE OF ORGANIC SILVER SALT, REDUCING AGENTS, PHOTOSENSITIVE SILVER HALIDE GRAINS AND BINDER | FUJI PHOTO FILM CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |