Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.64 |
| ▸ | IL1RN | P18510 | 1/20 | 0.64 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.64 |
| ▸ | PGR | P06401 | 4/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2444333 | 0.96 | KEAP1 (0.64) | KEAP1IL1RNERAP1PGRCYP19A1 | |
| SCHEMBL7171852 | 0.88 | GAA (0.58) | KEAP1IL1RNERAP1PGRCYP19A1 | |
| SCHEMBL28538527 | 0.85 | WDR5 (0.73) | KEAP1IL1RNERAP1PGRALDH1A1 | |
| SCHEMBL3791521 | 0.85 | PGR (0.81) | KEAP1IL1RNERAP1PGRCYP19A1 | |
| SCHEMBL29985647 | 0.83 | GAA (0.65) | KEAP1IL1RNERAP1PGRCYP19A1 | |
| SCHEMBL2133710 | 0.82 | CES1 (0.81) | KEAP1IL1RNERAP1PGRCYP19A1 | |
| SCHEMBL21462374 | 0.82 | PGR (0.57) | KEAP1IL1RNERAP1PGRCYP19A1 | |
| SCHEMBL9001184 | 0.82 | KEAP1 (0.79) | KEAP1IL1RNERAP1PGRCYP19A1 | |
| SCHEMBL6478779 | 0.81 | KEAP1 (0.60) | KEAP1IL1RNERAP1PGRCYP19A1 | |
| SCHEMBL3762452 | 0.81 | PGR (0.74) | KEAP1IL1RNERAP1PGRCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | KEAP1 1245/4885IL1RN 4803/4885ERAP1 4773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.