Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11577215 | 0.86 | CTSC (0.36) | ANPEPENPEPALDH1A1ACACBKMT2A | |
| SCHEMBL27598421 | 0.79 | ANPEP (0.56) | ANPEPENPEPALDH1A1FOLH1ACACB | |
| SCHEMBL2294263 | 0.79 | ALDH1A1 (0.50) | ANPEPENPEPALDH1A1FOLH1ACACB | |
| SCHEMBL9404074 | 0.77 | CYP1A2 (0.45) | ANPEPALDH1A1 | |
| SCHEMBL11567658 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TP53KMT2AKDM4EMEN1 | |
| SCHEMBL27751805 | 0.76 | ANPEP (0.62) | ANPEPENPEPALDH1A1FOLH1ACACB | |
| SCHEMBL7132237 | 0.74 | ANPEP (0.51) | ANPEPENPEPALDH1A1FOLH1ACACB | |
| SCHEMBL11133642 | 0.73 | ALDH1A1 (0.41) | ALDH1A1TSHRKMT2AMEN1MAPT | |
| SCHEMBL11565407 | 0.73 | CYP1A2 (0.41) | ALDH1A1KMT2AMEN1APEX1DPP4 | |
| SCHEMBL11565761 | 0.73 | TRPA1 (0.41) | ALDH1A1KMT2AMEN1SMN1; SMN2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1612868-A | Ethylene derivative and use as phophatidase | YANG JI CHEMICAL COMPANY LTD (KR) | 2005-05-04 | — | — | CN | disclosed |
| US-20050075345-A1 | Novel inhibitor compounds specific of secreted non-pancreatic human a<sb>2</sb>phospholipase of group II | YANG JI CHEMICAL COMPANY LTD. (KR) | 2005-04-07 | — | — | US | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| US-4105653-A | HETERYL-AZO-PHENYL DISPERSE DYESTUFFS CONTAINING A Z-SUBSTITUTED BENZOLYLOXYALKYL RADICAL, WHEREIN Z IS 2-CYANOVINYL 2-CYANOETHYL OR 2-CHLORO-2-CYANOETHYL | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1978-08-08 | — | — | US | disclosed |
| US-3987027-A | DISPERSE AZO DYES | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1976-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075345-A1 | Novel inhibitor compounds specific of secreted non-pancreatic human a<sb>2</sb>phospholipase of group II | AMY2A, PNLIP, IAPP | ANPEP 139/4885ENPEP 181/4885ALDH1A1 3782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.