Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.40 |
| ▸ | SOD3 | P08294 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6566169 | 0.95 | GBA1 (0.43) | GBA1GNAI3GNAO1GNAI1SOD3 | |
| SCHEMBL1583492 | 0.95 | GBA1 (0.43) | GBA1GNAI3GNAO1GNAI1SOD3 | |
| Hydrochloric Acid SCHEMBL7528001 | 0.94 | SOD3 (0.44) | GBA1GNAI3GNAO1GNAI1SOD3 | |
| Hydrochloric Acid SCHEMBL6479261 | 0.94 | SOD3 (0.44) | GBA1GNAI3GNAO1GNAI1SOD3 | |
| SCHEMBL161338 | 0.94 | MEN1 (0.43) | GBA1GNAI3GNAO1GNAI1SOD3 | |
| Bromide SCHEMBL28435713 | 0.92 | MEN1 (0.42) | GBA1GNAI3GNAO1GNAI1SOD3 | |
| Hydrochloric Acid SCHEMBL1662690 | 0.92 | MEN1 (0.42) | GBA1GNAI3GNAO1GNAI1SOD3 | |
| SCHEMBL1583265 | 0.89 | MEN1 (0.49) | GBA1GNAI3GNAO1GNAI1SOD3 | |
| Bromide SCHEMBL28431073 | 0.87 | MEN1 (0.47) | GBA1GNAI3GNAO1GNAI1SOD3 | |
| SCHEMBL1583740 | 0.81 | MEN1 (0.35) | GNAI3GNAO1GNAI1SOD3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075345-A1 | Novel inhibitor compounds specific of secreted non-pancreatic human a<sb>2</sb>phospholipase of group II | YANG JI CHEMICAL COMPANY LTD. (KR) | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075345-A1 | Novel inhibitor compounds specific of secreted non-pancreatic human a<sb>2</sb>phospholipase of group II | AMY2A, PNLIP, IAPP | GBA1 207/4885GNAI3 1140/4885GNAO1 1577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.