Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 5/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 3/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6481410 | 0.88 | PPARA (0.34) | S1PR1PPARAADORA3ADORA2AADORA1 | |
| SCHEMBL6493493 | 0.88 | CTSS (0.40) | S1PR1MMP1MMP3CTSSGHSR | |
| SCHEMBL6480795 | 0.87 | F2 (0.39) | — | |
| SCHEMBL6480782 | 0.85 | GHSR (0.46) | GHSR | |
| SCHEMBL6490939 | 0.85 | ALDH1A1 (0.32) | S1PR1PPARAADORA3ADORA2AADORA1 | |
| SCHEMBL6493904 | 0.81 | S1PR1 (0.40) | S1PR1 | |
| SCHEMBL6489933 | 0.80 | GHSR (0.37) | PPARAPPARGCTSSGHSR | |
| SCHEMBL6482638 | 0.80 | S1PR1 (0.39) | S1PR1PPARAPPARGMMP1MMP3 | |
| SCHEMBL6491275 | 0.80 | GHSR (0.37) | PPARAADORA3ADORA2AADORA1PPARG | |
| SCHEMBL6483067 | 0.78 | HPGDS (0.44) | MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261332-A1 | Sulfonamides and uses thereof | ELIXIR PHARMACEUTICALS, INC. | 2005-11-24 | — | — | US | disclosed |
| US-20050148776-A1 | Process for asymmetric hydrogenation of hexahydroquinoline salts | DSM IP ASSETS B.V. (NL) | 2005-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261332-A1 | Sulfonamides and uses thereof | GLS2, STS, ABAT | S1PR1 2194/4885PPARA 174/4885ADORA3 4437/4885 |
| US-20050148776-A1 | Process for asymmetric hydrogenation of hexahydroquinoline salts | HRH1, HRH4, HRH2 | S1PR1 2013/4885PPARA 4841/4885ADORA3 758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.