Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6479818 | 0.82 | MAPT (0.38) | MAPTTDP1MAPK1RAB9ALMNA | |
| SCHEMBL12377285 | 0.78 | BRAF (0.37) | MAPTTDP1MAPK1BRAFRAB9A | |
| SCHEMBL13726047 | 0.77 | BRAF (0.37) | MAPTMAPK1BRAFLMNAHTT | |
| SCHEMBL6492241 | 0.77 | ALDH1A1 (0.37) | MAPTTDP1MAPK1RAB9ALMNA | |
| SCHEMBL6651812 | 0.76 | KDM4E (0.37) | MAPTTDP1RAB9ALMNAHTT | |
| SCHEMBL29565106 | 0.76 | KDM4E (0.37) | MAPTTDP1RAB9ALMNAHTT | |
| SCHEMBL9928123 | 0.75 | BRAF (0.35) | MAPTTDP1BRAFRAB9ALMNA | |
| SCHEMBL1984131 | 0.73 | EDNRA (0.33) | MAPTBRAFRAB9ALMNAHTT | |
| SCHEMBL12659492 | 0.72 | MAPT (0.35) | MAPTTDP1MAPK1RAB9ALMNA | |
| SCHEMBL7115389 | 0.71 | KMT2A (0.36) | MAPTTDP1BRAFLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6863843-B2 | Naphthopyran compounds, photoresponsive compositions and lenses | VISION-EASE LENS, INC. (US) | 2005-03-08 | — | — | US | disclosed |
| US-20020080451-A1 | Novel naphthopyran compounds, photoresponsive compositions and lenses | VISION-EASE LENS, INC. | 2002-06-27 | — | — | US | disclosed |