Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29565106 | 1.00 | KDM4E (0.37) | KDM4EALDH1A1HPGDMEN1LMNA | |
| SCHEMBL5178952 | 0.94 | MEN1 (0.36) | KDM4EALDH1A1HPGDMEN1LMNA | |
| SCHEMBL1984131 | 0.90 | EDNRA (0.33) | KDM4EALDH1A1HPGDMEN1LMNA | |
| SCHEMBL5178231 | 0.83 | L3MBTL1 (0.38) | KDM4EALDH1A1HPGDMEN1LMNA | |
| SCHEMBL6172997 | 0.79 | PLA2G2A (0.38) | KDM4EALDH1A1HPGDMEN1LMNA | |
| SCHEMBL6648587 | 0.79 | HIF1A (0.33) | KDM4EALDH1A1HPGDMEN1LMNA | |
| SCHEMBL29565427 | 0.79 | HIF1A (0.33) | KDM4EALDH1A1HPGDMEN1LMNA | |
| SCHEMBL14293568 | 0.78 | EDNRA (0.36) | KDM4EALDH1A1MEN1LMNACYP2C9 | |
| SCHEMBL6649206 | 0.78 | MEN1 (0.35) | KDM4EALDH1A1HPGDMEN1LMNA | |
| SCHEMBL5101722 | 0.77 | KDM4E (0.36) | KDM4EALDH1A1HPGDMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12285922-B2 | Method for making photofunctional contact lenses | ALCON INC. (CH) | 2025-04-29 | — | — | US | claimed |
| EP-4313567-B1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | ALCON INC (CH) | 2025-01-29 | — | — | EP | claimed |
| US-12111443-B2 | Method for making photochromic contact lenses | ALCON INC. (CH) | 2024-10-08 | — | — | US | claimed |
| US-11945895-B2 | Photochromic polydiorganosiloxane vinylic crosslinkers | ALCON INC. (CH) | 2024-04-02 | — | — | US | claimed |
| CN-115605529-B | Photochromic polydiorganosiloxane vinyl cross-linking agent | 爱尔康公司 | 2024-03-26 | — | — | CN | claimed |
| EP-4118134-B1 | PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS | ALCON INC (CH) | 2024-02-28 | — | — | EP | claimed |
| EP-4313567-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | Alcon Inc. (CH) | 2024-02-07 | — | — | EP | claimed |
| EP-4304842-A1 | METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES | Alcon Inc. (CH) | 2024-01-17 | — | — | EP | claimed |
| EP-4304843-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | Alcon Inc. (CH) | 2024-01-17 | — | — | EP | claimed |
| US-11833771-B2 | Method for making photochromic contact lenses | ALCON INC. (CH) | 2023-12-05 | — | — | US | claimed |
| US-20220339895-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | ALCON INC. (CH) | 2022-10-27 | — | — | US | claimed |
| WO-2022189941-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | ALCON INC. (CH) | 2022-09-15 | — | — | WO | claimed |
| US-20220281193-A1 | METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES | ALCON INC. (CH) | 2022-09-08 | — | — | US | claimed |
| US-20220283338-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | ALCON INC. (CH) | 2022-09-08 | — | — | US | claimed |
| US-20210284806-A1 | PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS | ALCON INC. (CH) | 2021-09-16 | — | — | US | claimed |
| WO-2021181341-A1 | PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS | ALCON INC. (CH) | 2021-09-16 | — | — | WO | claimed |
| WO-2021181307-A1 | PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS | ALCON INC. (CH) | 2021-09-16 | — | — | WO | claimed |
| US-20210284778-A1 | PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS | ALCON INC (CH) | 2021-09-16 | — | — | US | claimed |
| EP-0835870-B1 | Photochromic substituted naphthopyrans | PPG IND OHIO INC (US) | 2004-03-03 | — | — | EP | claimed |
| EP-0835870-A1 | Photochromic substituted naphthopyrans | PPG INDUSTRIES, INC. (US) | 1998-04-15 | — | — | EP | claimed |