Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6492241 | 0.88 | ALDH1A1 (0.37) | MAPTTDP1MAPK1KDM4EALDH1A1 | |
| SCHEMBL12659492 | 0.83 | MAPT (0.35) | MAPTTDP1MAPK1KDM4EALDH1A1 | |
| SCHEMBL6480463 | 0.82 | MAPT (0.35) | MAPTTDP1MAPK1KDM4EALDH1A1 | |
| SCHEMBL10102269 | 0.81 | MAPT (0.36) | MAPTTDP1MAPK1KDM4EALDH1A1 | |
| SCHEMBL7533658 | 0.78 | PIK3CA (0.37) | MAPTMAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL7528995 | 0.78 | ALDH1A1 (0.37) | KDM4EALDH1A1HPGDKMT2AL3MBTL1 | |
| SCHEMBL10106931 | 0.76 | MAPT (0.39) | MAPTTDP1MAPK1KDM4EALDH1A1 | |
| SCHEMBL6479062 | 0.76 | ALDH1A1 (0.34) | MAPTTDP1MAPK1KDM4EALDH1A1 | |
| SCHEMBL10102406 | 0.73 | SLC2A1 (0.36) | MAPTKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL7528300 | 0.73 | PKM (0.37) | MAPTMAPK1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6863843-B2 | Naphthopyran compounds, photoresponsive compositions and lenses | VISION-EASE LENS, INC. (US) | 2005-03-08 | — | — | US | disclosed |
| US-20020080451-A1 | Novel naphthopyran compounds, photoresponsive compositions and lenses | VISION-EASE LENS, INC. | 2002-06-27 | — | — | US | disclosed |