Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6479818 | 0.88 | MAPT (0.38) | ALDH1A1MAPTTDP1MAPK1KMT2A | |
| SCHEMBL6480463 | 0.77 | MAPT (0.35) | ALDH1A1MAPTTDP1MAPK1KMT2A | |
| SCHEMBL6479062 | 0.73 | ALDH1A1 (0.34) | ALDH1A1MAPTTDP1MAPK1KMT2A | |
| SCHEMBL12659492 | 0.72 | MAPT (0.35) | ALDH1A1MAPTTDP1MAPK1KMT2A | |
| SCHEMBL5550993 | 0.72 | MAPT (0.38) | ALDH1A1MAPTMAPK1KMT2ALMNA | |
| SCHEMBL10102269 | 0.71 | MAPT (0.36) | ALDH1A1MAPTTDP1MAPK1LMNA | |
| SCHEMBL13726047 | 0.71 | BRAF (0.37) | ALDH1A1MAPTMAPK1KMT2ALMNA | |
| SCHEMBL24620628 | 0.71 | APP (0.38) | ALDH1A1MAPTMAPK1KMT2ALMNA | |
| SCHEMBL7936515 | 0.71 | KEAP1 (0.42) | ALDH1A1MAPTKMT2ARAB9AKDM4E | |
| SCHEMBL7971698 | 0.71 | MAPT (0.38) | ALDH1A1MAPTMAPK1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6863843-B2 | Naphthopyran compounds, photoresponsive compositions and lenses | VISION-EASE LENS, INC. (US) | 2005-03-08 | — | — | US | disclosed |
| US-20020080451-A1 | Novel naphthopyran compounds, photoresponsive compositions and lenses | VISION-EASE LENS, INC. | 2002-06-27 | — | — | US | disclosed |