SCHEMBL648243

SCHEMBL648243

c1ccc(CP(c2ccccc2)c2cccc3ccccc23)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.37
CA12 O43570 1/20 0.36
CA3 P07451 1/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
ALDH1A1 P00352 2/20 0.35
TSHR P16473 2/20 0.35
HSD17B10 Q99714 2/20 0.35
RECQL P46063 1/20 0.35
KDM4E B2RXH2 1/20 0.34
GSK3B P49841 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
CYP2A6 P11509 1/20 0.33
ACP3 P15309 1/20 0.33
KCNH2 Q12809 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27519474 0.95 TDP1 (0.39) TDP1CA12CA3CA4CA6
SCHEMBL8846547 0.83 TDP1 (0.40) TDP1CA12CA3CA4CA6
SCHEMBL22392090 0.83 MAPT (0.37) TDP1ALDH1A1TSHRHSD17B10KDM4E
SCHEMBL29882515 0.83 MAPT (0.37) TDP1ALDH1A1TSHRHSD17B10KDM4E
SCHEMBL27739229 0.83 KCNH2 (0.39) TDP1CA12CA3CA4CA6
SCHEMBL27932138 0.80 CA12 (0.44) TDP1CA12CA3CA4CA6
SCHEMBL15659078 0.80 TDP1 (0.38) TDP1CA12CA3CA4CA6
SCHEMBL6678949 0.79 ALDH1A1 (0.37) TDP1ALDH1A1TSHRHSD17B10KDM4E
SCHEMBL10757313 0.76 TDP1 (0.35) TDP1CA12CA3CA4CA6
SCHEMBL230856 0.76 TDP1 (0.43) TDP1CA12CA7CA14ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200385570-A1 POLYCARBONATE COMPOSITIONS BASF SE (DE) 2020-12-10 US claimed
EP-3710145-A1 POLYCARBONATE COMPOSITIONS BASF SE (DE) 2020-09-23 EP claimed
CN-111328293-A Polycarbonate compositions 巴斯夫欧洲公司 2020-06-23 CN claimed
US-6476178-B1 Polycarbonate resin composition IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-11-05 US claimed
US-20260125537-A1 POLYCARBONATE RESIN COMPOSITION MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2026-05-07 US disclosed
US-12570837-B2 Polycarbonate resin composition and molded article IDEMITSU KOSAN CO., LTD. (JP) 2026-03-10 US disclosed
EP-4692233-A1 POLYCARBONATE RESIN COMPOSITION Mitsubishi Engineering-Plastics Corporation (JP) 2026-02-11 EP disclosed
EP-3604443-B1 POLYCARBONATE RESIN COMPOSITION AND MOLDED BODY IDEMITSU KOSAN CO (JP) 2025-10-15 EP disclosed
US-12398266-B2 Polycarbonate resin composition IDEMITSU KOSAN CO., LTD. (JP) 2025-08-26 US disclosed
EP-4596628-A1 POLYCARBONATE RESIN COMPOSITION Mitsubishi Engineering-Plastics Corporation (JP) 2025-08-06 EP disclosed
US-20250205637-A1 GAS SEPARATION MEMBRANE IDEMITSU KOSAN CO., LTD. (JP) 2025-06-26 US disclosed
EP-4556507-A1 POLYCARBONATE-POLYORGANOSILOXANE COPOLYMER, POLYCARBONATE RESIN COMPOSITION AND MOLDED BODY Idemitsu Kosan Co.,Ltd. (JP) 2025-05-21 EP disclosed
US-4670479-A BLEND INCLUDING RGANIC PHOSPHINE AND PARTIAL ESTER OF MONOBASIC FATTY ACID AND POLYHYDRIC ALCOHOL TEIJIN CHEMICALS, LTD. (JP) 1987-06-02 US disclosed
EP-0213413-A1 Polycarbonate resin composition and its use in optical applications Teijin Chemicals, Ltd. (JP) 1987-03-11 EP disclosed
US-4627949-A PHOSPHINE STABILIZER BAYER AKTIENGESELLSCHAFT (DE) 1986-12-09 US disclosed
US-RE32046-E PHOSPHINES IN OXETANYL-ALKOXYSILANES OR OXETANYL= =METHYL CARBOXYESTERS, HEAT AND OXIDATION RESISTANCE BAYER AKTIENGESELLSCHAFT (DE) 1985-12-10 US disclosed
EP-0143906-A1 Process for preparing stabilized polycarbonate moulded articles by vented injection moulding or vented extrusion moulding BAYER AG (DE) 1985-06-12 EP disclosed
EP-0043998-B1 STABILIZER MIXTURES, THEIR USE IN STABILIZING THERMOPLASTIC POLYCARBONATES, AND STABILIZED THERMOPLASTIC POLYCARBONATES BAYER AG (DE) 1984-04-18 EP disclosed
US-4367303-A Solutions for stabilizing thermoplastic polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 1983-01-04 US disclosed
EP-0043998-A2 Stabilizer mixtures, their use in stabilizing thermoplastic polycarbonates, and stabilized thermoplastic polycarbonates BAYER AG (DE) 1982-01-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570837-B2 Polycarbonate resin composition and molded article ERCC1, POT1, BMI1 TDP1 1001/4885CA12 3963/4885CA3 3398/4885
US-20260125537-A1 POLYCARBONATE RESIN COMPOSITION COL1A1, RER1, GSTP1 TDP1 462/4885CA12 2842/4885CA3 806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.