Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 16/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MASP2 | O00187 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8810549 | 0.85 | HTR2C (0.54) | F2F10PLGPLATPRSS1 | |
| SCHEMBL23793372 | 0.82 | F2 (0.59) | F2HTR2CHTR2BMASP2 | |
| SCHEMBL6477871 | 0.81 | F2 (0.54) | F2F10PLGPLATPRSS1 | |
| SCHEMBL8393443 | 0.80 | ALDH1A1 (0.59) | F2HTR2CHTR2BCYP3A4CYP2C9 | |
| SCHEMBL30179363 | 0.80 | ALDH1A1 (0.59) | F2HTR2CHTR2BCYP3A4CYP2C9 | |
| SCHEMBL8535634 | 0.80 | ALDH1A1 (0.59) | F2HTR2CHTR2BCYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL9275339 | 0.79 | POLB (0.57) | F2HTR2CHTR2BCYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL9275345 | 0.79 | POLB (0.57) | F2HTR2CHTR2BCYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL27541627 | 0.79 | ALDH1A1 (0.58) | F2HTR2CHTR2BCYP3A4CYP2C9 | |
| SCHEMBL13263366 | 0.79 | HTR2C (0.48) | F2KDM4EHTR2CHTR2BCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900319-B2 | Thrombin inhibitors | ABBOTT GMBH & CO. KG (DE) | 2005-05-31 | — | — | US | disclosed |
| US-20020169318-A1 | Novel thrombin inhibitors | ABBVIE DEUTSCHLAND GMBH & CO KG (DE) | 2002-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020169318-A1 | Novel thrombin inhibitors | TFPI, SERPINC1, F11 | F2 5/4885F10 23/4885PLG 78/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.