SCHEMBL648594

SCHEMBL648594

CC(=O)CC(=O)OCC(COC(=O)CC(C)=O)OC(=O)CC(C)=O

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
LMNA P02545 1/20 0.47
MGAM O43451 1/20 0.46
GAA P10253 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46
PRKCA P17252 4/20 0.42
PRKCE Q02156 1/20 0.40
PRKCQ Q04759 1/20 0.40
PRKCD Q05655 1/20 0.40
LPAR3 Q9UBY5 5/20 0.38
LPAR1 Q92633 3/20 0.38
ENPP2 Q13822 3/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
LPAR2 Q9HBW0 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25624155 0.92 MGAM (0.45) ALDH1A1LMNAMGAMGAASI
SCHEMBL17190720 0.91 ALDH1A1 (0.41) ALDH1A1LMNAMGAMGAASI
SCHEMBL491474 0.90 PRKCA (0.54) PRKCAPRKCEPRKCQPRKCD
SCHEMBL272764 0.88 TSHR (0.50) ALDH1A1LMNAMGAMGAASI
SCHEMBL30531667 0.88 PRKCA (0.45) ALDH1A1LMNAMGAMGAASI
SCHEMBL25465012 0.87 MGAM (0.39) ALDH1A1LMNAMGAMGAASI
SCHEMBL18089622 0.87 PRKCA (0.47) ALDH1A1LMNAMGAMGAASI
SCHEMBL3244216 0.86 TSHR (0.49) ALDH1A1LMNAMGAMGAASI
SCHEMBL21815471 0.85 MGAM (0.38) ALDH1A1LMNAMGAMGAASI
SCHEMBL24119154 0.84 GAA (0.36) ALDH1A1LMNAMGAMGAASI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 488 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4574871-A1 CURABLE POLYMER COMPOSITIONS COMPRISING ALDIMINES, POLYISOCYANATES AND COMPOUNDS WITH ACTIVATED METHYLENE GROUPS Sika Technology AG (CH) 2025-06-25 EP claimed
EP-4574867-A1 CURABLE POLYMER COMPOSITIONS CONTAINING ISOCYANATES, ALDIMINES AND COMPOUNDS HAVING ACTIVATED METHYLENE GROUPS Sika Technology AG (CH) 2025-06-25 EP claimed
US-11890264-B2 Migraine prevention and treatment UNIVERSITATS-KINDERSPITAL BEIDER BASEL (CH) 2024-02-06 US claimed
US-11732165-B2 Low-temperature curable compositions EASTMAN CHEMICAL COMPANY (US) 2023-08-22 US claimed
WO-2023139231-A1 RESIN COMPOSITION ARXADA AG (CH) 2023-07-27 WO claimed
EP-3662044-B1 DETERGENT ADDITIVE DOW GLOBAL TECHNOLOGIES LLC (US) 2022-08-03 EP claimed
US-11370995-B2 Detergent additive DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-28 US claimed
US-20220056171-A1 Isocyanate Free Binder ARXADA AG (CH) 2022-02-24 US claimed
CN-111010876-B Encapsulation method 陶氏环球技术有限责任公司 2022-01-11 CN claimed
CN-110959036-B Detergent additive 陶氏环球技术有限责任公司 2022-01-04 CN claimed
EP-0971989-A1 NON-POLYMERIC ACETOACETATES AS ADHESION PROMOTING COALESCING AGENTS EASTMAN CHEMICAL COMPANY (US) 2000-01-19 EP claimed
US-5945489-A Liquid oligomers containing unsaturation ASHLAND, INC. (US) 1999-08-31 US claimed
US-5922790-A ACETOACETATE ESTERS AS ADDED TO WATERBORNE COMPOSITIONS CONTAINING ALKYD RESINS; IMPROVED ADHESION, ESPECIALLY TO CORRODED METAL SUBSTRATES EASTMAN CHEMICAL COMPANY (US) 1999-07-13 US claimed
WO-1998030639-A1 NON-POLYMERIC ACETOACETATES AS ADHESION PROMOTING COALESCING AGENTS EASTMAN CHEMICAL COMPANY (US) 1998-07-16 WO claimed
WO-1996012579-A1 FOUNDRY MIXES AND THEIR USES ASHLAND INC. (US) 1996-05-02 WO claimed
US-5459178-A Aggregate and binder comprising an acetoacetate ester, di-or triacrylate and a liquid tertiary amine catalyst; foundry shapes made by no-bake process ASHLAND INC. (US) 1995-10-17 US claimed
US-5420335-A Intravenous feeding BIRKHAHN RONALD H (US) 1995-05-30 US claimed
WO-1995009144-A1 NUTRITIVE WATER SOLUBLE GLYCEROL ESTERS OF HYDROXY BUTYRIC ACID EASTMAN CHEMICAL COMPANY (US) 1995-04-06 WO claimed
WO-1995009146-A1 PARENTERAL NUTRIENTS BASED ON WATER SOLUBLE GLYCEROL BISACETOACETATES EASTMAN CHEMICAL COMPANY (US) 1995-04-06 WO claimed
US-5017649-A Low temperature crosslinking EASTMAN KODAK COMPANY (US) 1991-05-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11890264-B2 Migraine prevention and treatment ACACA, ACACB, HBB ALDH1A1 763/4885LMNA 1124/4885MGAM 2155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.