SCHEMBL6486333

SCHEMBL6486333

CC1(C)CC(O)CC(C)(C)N1OC(=O)c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.70
TSHR P16473 3/20 0.70
ALDH1A1 P00352 1/20 0.52
ESR1 P03372 1/20 0.52
HSD17B10 Q99714 1/20 0.52
GAA P10253 2/20 0.48
MAPT P10636 1/20 0.47
NPSR1 Q6W5P4 1/20 0.46
MEN1 O00255 3/20 0.45
LMNA P02545 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
F2 P00734 1/20 0.40
HTR3E A5X5Y0 1/20 0.39
HTR3B O95264 1/20 0.39
CHRNA7 P36544 1/20 0.39
HTR3A P46098 1/20 0.39
HTR3D Q70Z44 1/20 0.39
HTR3C Q8WXA8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4308950 0.85 KMT2A (0.75) KMT2ATSHRALDH1A1ESR1HSD17B10
SCHEMBL6486327 0.85 TSHR (0.52) KMT2ATSHRALDH1A1ESR1HSD17B10
SCHEMBL1138721 0.85 KMT2A (0.84) KMT2ATSHRALDH1A1ESR1HSD17B10
SCHEMBL9744197 0.84 KMT2A (0.82) KMT2ATSHRALDH1A1ESR1HSD17B10
SCHEMBL4106959 0.82 KMT2A (0.71) KMT2ATSHRALDH1A1ESR1HSD17B10
SCHEMBL13110327 0.82 KMT2A (1.00) KMT2ATSHRALDH1A1ESR1HSD17B10
SCHEMBL9745635 0.81 KMT2A (0.78) KMT2ATSHRALDH1A1ESR1HSD17B10
SCHEMBL4625144 0.81 KMT2A (0.61) KMT2ATSHRALDH1A1ESR1HSD17B10
SCHEMBL9440018 0.80 KMT2A (0.68) KMT2ATSHRALDH1A1ESR1HSD17B10
SCHEMBL13110344 0.79 GAA (0.73) KMT2ATSHRALDH1A1ESR1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024149166-A1 LOW-FLUIDITY PACKAGING ADHESIVE FILM SPECIALLY FOR HETEROJUNCTION SOLAR CELL ASSEMBLY AND PREPARATION METHOD FOR SAME 浙江祥邦科技股份有限公司 2024-07-18 WO claimed
US-20210388150-A1 A PROCESS FOR PRODUCING A POLYURETHANE ELASTOMER COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2021-12-16 US claimed
EP-3883982-A1 A PROCESS FOR PRODUCING A POLYURETHANE ELASTOMER Covestro Intellectual Property GmbH & Co. KG (DE) 2021-09-29 EP claimed
US-6962763-B2 Silver-free black-and-white thermographic materials EASTMAN KODAK COMPANY (US) 2005-11-08 US claimed
US-20050186520-A1 SILVER-FREE BLACK-AND-WHITE THERMOGRAPHIC MATERIALS EASTMAN KODAK COMPANY 2005-08-25 US claimed
WO-2024149166-A1 LOW-FLUIDITY PACKAGING ADHESIVE FILM SPECIALLY FOR HETEROJUNCTION SOLAR CELL ASSEMBLY AND PREPARATION METHOD FOR SAME 浙江祥邦科技股份有限公司 2024-07-18 WO disclosed
US-20210388150-A1 A PROCESS FOR PRODUCING A POLYURETHANE ELASTOMER COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2021-12-16 US disclosed
EP-3883982-A1 A PROCESS FOR PRODUCING A POLYURETHANE ELASTOMER Covestro Intellectual Property GmbH & Co. KG (DE) 2021-09-29 EP disclosed
US-6962763-B2 Silver-free black-and-white thermographic materials EASTMAN KODAK COMPANY (US) 2005-11-08 US disclosed
US-20050186520-A1 SILVER-FREE BLACK-AND-WHITE THERMOGRAPHIC MATERIALS EASTMAN KODAK COMPANY 2005-08-25 US disclosed
EP-1404338-A1 ADENOSINE ANALOGUES FOR THE TREATMENT OF THE INSULIN RESISTANCE SYNDROME AND DIABETES Aventis Pharma Deutschland GmbH (DE) 2004-04-07 EP disclosed
US-20030176390-A1 Methods of treating insulin resistance syndrome and diabetes HERLING ANDREAS (DE) 2003-09-18 US disclosed
US-20020099030-A1 Compounds having antihypertensive, cardioprotective anti-ischemic and antilipolytic properties AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2002-07-25 US disclosed
EP-0880540-B1 17-BETA-CYCLOPROPYL(AMINO/OXY) 4-AZA STEROIDS AS ACTIVE INHIBITORS OF TESTOSTERONE 5-ALPHA-REDUCTASE AND C17-20-LYASE AVENTIS PHARMA INC (US) 2002-06-12 EP disclosed
US-6376472-B1 N6-SUBSTITUTED ADENOSINES AVENTIS PHARMACEUTICALS, INC. 2002-04-23 US disclosed
US-6365597-B1 FOR THERAPY OF ANDROGEN AND ESTROGEN MEDIATED DISORDERS, INCLUDING BENIGN PROSTATIC HYPERPLASIA, ANDROGEN MEDIATED PROSTATE CANCER, ESTROGEN MEDIATED BREAST CANCER AND ACNE AVENTIS PHARMACEUTICALS INC. 2002-04-02 US disclosed
WO-2000023447-A1 ADENOSINE ANALOGUES HAVING ANTIHYPERTENSIVE, CARDIOPROTECTIVE, ANTI-ISCHEMIC ANTILIPOLYTIC PROPERTIES AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 2000-04-27 WO disclosed
EP-0912520-A4 COMPOUNDS HAVING ANTIHYPERTENSIVE, CARDIOPROTECTIVE, ANTI-ISCHEMIC AND ANTILIPOLYTIC PROPERTIES RHONE POULENC RORER PHARMA (US) 1999-10-06 EP disclosed
EP-0912520-A1 COMPOUNDS HAVING ANTIHYPERTENSIVE, CARDIOPROTECTIVE, ANTI-ISCHEMIC AND ANTILIPOLYTIC PROPERTIES RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) 1999-05-06 EP disclosed
WO-1998001426-A1 COMPOUNDS HAVING ANTIHYPERTENSIVE, CARDIOPROTECTIVE, ANTI-ISCHEMIC AND ANTILIPOLYTIC PROPERTIES RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1998-01-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030176390-A1 Methods of treating insulin resistance syndrome and diabetes IAPP, GPR119, INSR KMT2A 3621/4885TSHR 1927/4885ALDH1A1 1392/4885
US-20020099030-A1 Compounds having antihypertensive, cardioprotective anti-ischemic and antilipolytic properties HMGCR, TGFB1, APOB KMT2A 2439/4885TSHR 4041/4885ALDH1A1 388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.