Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 10/20 | 0.61 |
| ▸ | MMP2 | P08253 | 7/20 | 0.61 |
| ▸ | MMP14 | P50281 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5842347 | 0.85 | KDM4E (0.65) | MMP13MMP2MMP14KDM4EALDH1A1 | |
| SCHEMBL14245 | 0.83 | XDH (0.51) | MMP13MMP2MMP14KDM4EALDH1A1 | |
| SCHEMBL6478710 | 0.81 | MMP13 (0.64) | MMP13MMP2MMP14KDM4EALDH1A1 | |
| SCHEMBL6486903 | 0.81 | MMP13 (0.61) | MMP13MMP2MMP14KDM4EALDH1A1 | |
| SCHEMBL419130 | 0.81 | MMP13 (0.77) | MMP13MMP2MMP14KDM4EALDH1A1 | |
| SCHEMBL3500194 | 0.77 | MMP13 (0.75) | MMP13MMP2MMP14KDM4EALDH1A1 | |
| SCHEMBL15642864 | 0.76 | MMP13 (1.00) | MMP13MMP2MMP14KDM4EALDH1A1 | |
| SCHEMBL5738407 | 0.76 | RAB9A (0.81) | MMP13MMP2MMP14KDM4EALDH1A1 | |
| SCHEMBL829242 | 0.75 | KDM4E (0.76) | MMP13MMP2MMP14KDM4EALDH1A1 | |
| SCHEMBL3006436 | 0.75 | MMP13 (0.72) | MMP13MMP2MMP14KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6951880-B2 | Aryl and heteroaryl compounds as antibacterial and antifungal agents | GENELABS TECHNOLOGIES, INC. (US) | 2005-10-04 | — | — | US | disclosed |
| WO-2004047724-A2 | ARYL AND HETEROARYL COMPOUNDS AS ANTIBACTERIAL AND ANTIFUNGAL AGENTS | GENELABS TECHNOLOGIES, INC (US) | 2004-06-10 | — | — | WO | disclosed |
| US-20030220340-A1 | Aryl and heteroaryl compounds as antibacterial and antifungal agents | GLAXOSMITHKLINE LLC | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220340-A1 | Aryl and heteroaryl compounds as antibacterial and antifungal agents | AADAC, ERG28, LSS | MMP13 2471/4885MMP2 2120/4885MMP14 3247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.