Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678971 | 0.84 | TP53 (0.39) | ALDH1A1SMN1; SMN2MEN1CYP3A4CYP2C9 | |
| SCHEMBL6487391 | 0.83 | KDM4E (0.41) | F2ALDH1A1MEN1CYP3A4CYP2C9 | |
| SCHEMBL6489441 | 0.83 | F2 (0.44) | F2ALDH1A1SMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL6492221 | 0.79 | F2 (0.39) | F2SMN1; SMN2MEN1CYP3A4CYP2C9 | |
| SCHEMBL6796112 | 0.78 | MEN1 (0.41) | F2MEN1KMT2ATDP1 | |
| SCHEMBL6645327 | 0.77 | ALDH1A1 (0.43) | F2ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6648457 | 0.76 | F2 (0.40) | F2ALDH1A1MEN1CYP3A4KMT2A | |
| SCHEMBL25920624 | 0.75 | CHRM2 (0.44) | F2ALDH1A1SMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL9407535 | 0.75 | MEN1 (0.50) | F2ALDH1A1SMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL6796397 | 0.73 | SMO (0.41) | F2ALDH1A1KDM4EHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
| US-20040133008-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-08 | — | — | US | disclosed |
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | APOB, APOL1, SCARB1 | F2 1399/4885ALDH1A1 1427/4885SMN1; SMN2 2504/4885 |
| US-20040133008-A1 | Amide compounds | APOB, APOL1, LDLR | F2 1415/4885ALDH1A1 2174/4885SMN1; SMN2 1836/4885 |
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | APOB, APOL1, CTRB2 | F2 62/4885ALDH1A1 1603/4885SMN1; SMN2 1921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.