Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 7/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | PRKX | P51817 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6498814 | 0.92 | S1PR1 (0.39) | DCTPP1AGTR1AGTR2S1PR1PRKX | |
| SCHEMBL6491233 | 0.90 | MRGPRX4 (0.40) | DCTPP1P2RX3SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL6488028 | 0.88 | AGTR1 (0.40) | DCTPP1AGTR1AGTR2SMN1; SMN2KDM4E | |
| SCHEMBL7200216 | 0.87 | PIK3C2B (0.41) | DCTPP1AGTR1AGTR2SMN1; SMN2NPC1 | |
| SCHEMBL6490528 | 0.86 | DCTPP1 (0.42) | DCTPP1P2RX3SMN1; SMN2ALDH1A1VDR | |
| SCHEMBL6499570 | 0.85 | BCL2 (0.42) | DCTPP1SMN1; SMN2MAPT | |
| SCHEMBL7196400 | 0.83 | PIK3C2B (0.40) | DCTPP1AGTR1AGTR2S1PR1PRKX | |
| SCHEMBL6491685 | 0.82 | FABP3 (0.46) | SMN1; SMN2 | |
| SCHEMBL6489346 | 0.81 | MRGPRX4 (0.46) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6493027 | 0.80 | MCL1 (0.43) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | DCTPP1 1534/4885P2RX3 2660/4885AGTR1 2045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.