Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | PIK3C2B | O00750 | 3/20 | 0.37 |
| ▸ | BCL2 | P10415 | 5/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.34 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.34 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.33 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6495279 | 0.93 | MAPT (0.36) | RENPIK3C2BALOX5APDCTPP1SLC16A3 | |
| SCHEMBL6501064 | 0.91 | PIK3C2B (0.38) | PIK3C2BBCL2MCL1PPARGDCTPP1 | |
| SCHEMBL6490992 | 0.90 | BCL2 (0.45) | PIK3C2BBCL2MCL1 | |
| SCHEMBL6491725 | 0.90 | PIK3C2B (0.37) | PIK3C2BBCL2MCL1ALOX5APSLC22A12 | |
| SCHEMBL6503787 | 0.88 | PIK3C2B (0.38) | PIK3C2BBCL2MCL1PPARGALOX5AP | |
| SCHEMBL6489176 | 0.85 | BCL2 (0.38) | BCL2MCL1DCTPP1 | |
| SCHEMBL6492258 | 0.85 | ALDH1A1 (0.35) | PIK3C2BPPARGDCTPP1 | |
| SCHEMBL6492991 | 0.82 | DCTPP1 (0.36) | PIK3C2BBCL2MCL1DCTPP1 | |
| SCHEMBL6489538 | 0.81 | MCL1 (0.42) | MCL1 | |
| SCHEMBL6491005 | 0.81 | BCL2 (0.47) | PIK3C2BBCL2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | REN 331/4885PIK3C2B 2433/4885BCL2 774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.