SCHEMBL6489201

SCHEMBL6489201

CCOc1ccc(Cn2c(C)nc3c(C)cc(CO)cc32)c(Cl)c1

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DCTPP1 Q9H773 13/20 0.40
F2RL3 Q96RI0 1/20 0.39
MAPT P10636 2/20 0.36
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6491248 0.85 DCTPP1 (0.38) DCTPP1F2RL3MAPTL3MBTL1LMNA
SCHEMBL6490602 0.85 PPARG (0.41) DCTPP1HPGDL3MBTL1LMNASMN1; SMN2
SCHEMBL6488896 0.83 DCTPP1 (0.40) DCTPP1MAPTALDH1A1HPGDL3MBTL1
SCHEMBL6489346 0.82 MRGPRX4 (0.46) SMN1; SMN2
SCHEMBL6498814 0.81 S1PR1 (0.39) DCTPP1
SCHEMBL7196400 0.81 PIK3C2B (0.40) DCTPP1
SCHEMBL6490528 0.81 DCTPP1 (0.42) DCTPP1ALDH1A1LMNASMN1; SMN2
SCHEMBL7200216 0.80 PIK3C2B (0.41) DCTPP1SMN1; SMN2
SCHEMBL6487408 0.80 DCTPP1 (0.38) DCTPP1MAPTALDH1A1HPGDSMN1; SMN2
SCHEMBL6492577 0.80 DCTPP1 (0.41) DCTPP1ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050014812-A1 Benzimidazole compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2005-01-20 US disclosed
WO-2004108686-A2 BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-12-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050014812-A1 Benzimidazole compounds SLC5A1, SLC5A2, G6PD DCTPP1 1534/4885F2RL3 4305/4885MAPT 3168/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.