Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.38 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.37 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6489353 | 0.88 | PIK3C2B (0.38) | MRGPRX4PIK3C2BLMNASMN1; SMN2PTGER1 | |
| SCHEMBL6490645 | 0.84 | PTGDR (0.44) | NPSR1MRGPRX4CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6502432 | 0.82 | PPARG (0.42) | NPSR1MRGPRX4CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6494714 | 0.82 | KDM4C (0.44) | NPSR1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6498704 | 0.81 | P2RX3 (0.45) | MRGPRX4PPARGLMNASMN1; SMN2PTGER1 | |
| SCHEMBL6172911 | 0.81 | PPARG (0.48) | NPSR1MRGPRX4CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6490742 | 0.80 | CYP1A2 (0.38) | CYP1A2PIK3C2BLMNASMN1; SMN2HPGD | |
| SCHEMBL7172666 | 0.80 | PIK3C2B (0.42) | NPSR1MRGPRX4CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6498703 | 0.79 | LMNA (0.39) | NPSR1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6489619 | 0.79 | PIK3C2B (0.41) | NPSR1CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | NPSR1 4348/4885MRGPRX4 2443/4885CYP1A2 247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.