Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.34 |
| ▸ | ITGAL | P20701 | 1/20 | 0.34 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 2/20 | 0.33 |
| ▸ | LSS | P48449 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4848356 | 0.86 | METAP2 (0.37) | METAP2SCN9AGCGRHCRTR1HCRTR2 | |
| SCHEMBL4841746 | 0.84 | METAP2 (0.39) | METAP2SCN9AHCRTR1HCRTR2ITGB2 | |
| SCHEMBL14254856 | 0.84 | METAP2 (0.39) | METAP2SCN9AHCRTR1HCRTR2ITGB2 | |
| SCHEMBL4844861 | 0.84 | METAP2 (0.39) | METAP2SCN9AGCGRHCRTR1HCRTR2 | |
| SCHEMBL4841580 | 0.83 | METAP2 (0.39) | METAP2SCN9AGCGRHCRTR1HCRTR2 | |
| SCHEMBL4848499 | 0.82 | SCN9A (0.42) | METAP2SCN9AGCGRHCRTR1HCRTR2 | |
| SCHEMBL6489587 | 0.82 | METAP2 (0.37) | METAP2SCN9AHCRTR1HCRTR2ITGB2 | |
| SCHEMBL6478158 | 0.80 | UTS2R (0.37) | METAP2SCN9AGCGRCHRM4LIPE | |
| SCHEMBL4848518 | 0.80 | CCR5 (0.34) | METAP2CCR5GCGRCYP3A4LIPE | |
| SCHEMBL4885451 | 0.79 | EPHX2 (0.38) | METAP2SCN9ACHRM4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897225-B1 | Inhibitors of αLβ2 mediated cell adhesion | TANABE SEIYAKU CO., LTD. (JP) | 2005-05-24 | — | — | US | disclosed |