Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 14/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.46 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.45 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.45 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.45 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.45 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490857 | 1.00 | SLC6A3 (0.55) | SLC6A3SLC6A2SLC6A4CHRM2CHRM4 | |
| SCHEMBL6489548 | 0.89 | SLC6A3 (0.54) | SLC6A3SLC6A2SLC6A4CHRM2CHRM4 | |
| SCHEMBL21332404 | 0.88 | SLC6A3 (0.72) | SLC6A3SLC6A2SLC6A4CHRM5CHRM1 | |
| SCHEMBL1752641 | 0.88 | SLC6A2 (0.67) | SLC6A3SLC6A2SLC6A4CHRM2CHRM4 | |
| SCHEMBL1752640 | 0.88 | SLC6A2 (0.67) | SLC6A3SLC6A2SLC6A4CHRM2CHRM4 | |
| SCHEMBL1743636 | 0.87 | SLC6A3 (0.71) | SLC6A3SLC6A2SLC6A4CHRM5CHRM1 | |
| SCHEMBL16061721 | 0.86 | SLC6A3 (0.64) | SLC6A3SLC6A2SLC6A4CHRM2CHRM4 | |
| SCHEMBL6503784 | 0.85 | SLC6A2 (0.56) | SLC6A3SLC6A2SLC6A4CHRM2CHRM4 | |
| SCHEMBL6503781 | 0.85 | SLC6A2 (0.56) | SLC6A3SLC6A2SLC6A4CHRM2CHRM4 | |
| SCHEMBL6503574 | 0.84 | SLC6A3 (0.75) | SLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | APOB, APOL1, CTRB2 | SLC6A3 3942/4885SLC6A2 1801/4885SLC6A4 3899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.