SCHEMBL6490910

SCHEMBL6490910

CS(=O)(=O)c1ccc(C(=O)OC2=CC(=O)CCC2)c(Cl)c1Cn1nnc(-c2ccccc2)n1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.37
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
USP2 O75604 1/20 0.36
PKM P14618 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
THRB P10828 2/20 0.36
NPC1 O15118 3/20 0.36
SMN1; SMN2 Q16637 4/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ATM Q13315 1/20 0.35
MAPT P10636 1/20 0.35
TP53 P04637 1/20 0.35
CASP3 P42574 1/20 0.34
SENP8 Q96LD8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6489202 0.86
SCHEMBL6481368 0.86 HPGD (0.38) RAB9AMEN1KMT2AUSP2PKM
SCHEMBL6480897 0.85 HDAC6 (0.36) HDAC6ALDH1A1HTTMAPT
SCHEMBL6481669 0.82
SCHEMBL6491567 0.79 MEN1 (0.30) MEN1KMT2A
SCHEMBL6332845 0.79
SCHEMBL7655253 0.78 MAPT (0.36) RAB9AMEN1KMT2ANPC1SMN1; SMN2
SCHEMBL6492677 0.78 ALDH1A1 (0.32) ALDH1A1HTTMAPT
SCHEMBL6482084 0.76 ENPP2 (0.34) RAB9ANPC1
SCHEMBL6603722 0.76 MAPT (0.33) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050090398-A1 Novel tetrazole derivative useful as herbicides YANAGI AKIHIKO (JP) 2005-04-28 US disclosed
EP-1476437-A1 NOVEL TETRAZOLE DERIVATIVE USEFUL AS HERBICIDES Bayer CropScience AG (DE) 2004-11-17 EP disclosed
WO-2003066607-A1 NOVEL TETRAZOLE DERIVATIVE USEFUL AS HERBICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2003-08-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050090398-A1 Novel tetrazole derivative useful as herbicides DDT, TTI1, CYP1A1 RAB9A 599/4885MEN1 2766/4885KMT2A 1800/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.