Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6482370 | 0.86 | ALDH1A1 (0.38) | HDAC6HSD11B1PTGS2MAPTALDH1A1 | |
| SCHEMBL6492677 | 0.85 | ALDH1A1 (0.32) | MAPTALDH1A1HPGDHTT | |
| SCHEMBL6490910 | 0.85 | RAB9A (0.37) | HDAC6MAPTALDH1A1HTT | |
| SCHEMBL6332845 | 0.81 | — | — | |
| SCHEMBL6491567 | 0.80 | MEN1 (0.30) | — | |
| SCHEMBL6481669 | 0.80 | — | — | |
| SCHEMBL5184238 | 0.80 | ALDH1A1 (0.39) | MAPTALDH1A1HPGDPOLB | |
| SCHEMBL6326063 | 0.79 | — | — | |
| SCHEMBL6489202 | 0.79 | — | — | |
| SCHEMBL6435663 | 0.78 | THRB (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050090398-A1 | Novel tetrazole derivative useful as herbicides | YANAGI AKIHIKO (JP) | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090398-A1 | Novel tetrazole derivative useful as herbicides | DDT, TTI1, CYP1A1 | HDAC6 2268/4885HSD11B1 1187/4885PTGS2 4507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.