Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 8/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.69 |
| ▸ | APP | P05067 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 9/20 | 0.65 |
| ▸ | RAB9A | P51151 | 9/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | PKM | P14618 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.65 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15177306 | 0.89 | APP (0.73) | ALDH1A3ALDH1A1ALDH1A2APPNPC1 | |
| SCHEMBL24320031 | 0.84 | NPC1 (0.74) | ALDH1A3ALDH1A1ALDH1A2APPNPC1 | |
| SCHEMBL26603206 | 0.83 | APP (0.69) | ALDH1A3ALDH1A1ALDH1A2APPNPC1 | |
| SCHEMBL2904371 | 0.83 | APP (0.66) | ALDH1A3ALDH1A1ALDH1A2APPNPC1 | |
| SCHEMBL1985593 | 0.83 | APP (0.66) | ALDH1A3ALDH1A1ALDH1A2APPNPC1 | |
| SCHEMBL1726415 | 0.83 | APP (0.66) | ALDH1A3ALDH1A1ALDH1A2APPNPC1 | |
| SCHEMBL217156 | 0.83 | RAB9A (0.75) | ALDH1A3ALDH1A1ALDH1A2APPNPC1 | |
| SCHEMBL26603213 | 0.82 | APP (0.54) | ALDH1A3ALDH1A1ALDH1A2APPNPC1 | |
| SCHEMBL13325768 | 0.81 | ALDH1A3 (1.00) | ALDH1A3ALDH1A1ALDH1A2NPC1RAB9A | |
| Bromide SCHEMBL1726261 | 0.81 | NPC1 (0.65) | ALDH1A3ALDH1A1ALDH1A2APPNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250283038-A1 | COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2025-09-11 | — | — | US | claimed |
| EP-4511027-A1 | COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS | Université Paris Cité (FR) | 2025-02-26 | — | — | EP | claimed |
| WO-2023203163-A1 | COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS | UNIVERSITE PARIS CITE (FR) | 2023-10-26 | — | — | WO | claimed |
| EP-4265248-A1 | COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS | Université Paris Cité (FR) | 2023-10-25 | — | — | EP | claimed |
| US-20250283038-A1 | COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2025-09-11 | — | — | US | disclosed |
| EP-4511027-A1 | COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS | Université Paris Cité (FR) | 2025-02-26 | — | — | EP | disclosed |
| US-20240034723-A1 | PIPERIDINYL SMALL MOLECULE DEGRADERS OF HELIOS AND METHODS OF USE | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-02-01 | — | — | US | disclosed |
| WO-2023203163-A1 | COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS | UNIVERSITE PARIS CITE (FR) | 2023-10-26 | — | — | WO | disclosed |
| WO-2023203163-A1 | COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS | UNIVERSITE PARIS CITE (FR) | 2023-10-26 | — | — | WO | disclosed |
| EP-4265248-A1 | COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS | Université Paris Cité (FR) | 2023-10-25 | — | — | EP | disclosed |
| EP-4265248-A1 | COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS | Université Paris Cité (FR) | 2023-10-25 | — | — | EP | disclosed |
| CN-116669769-A | Piperidinyl small molecule degradants of HELIOS and methods of use | 达纳－法伯癌症研究所公司 | 2023-08-29 | — | — | CN | disclosed |
| EP-4228651-A1 | PIPERIDINYL SMALL MOLECULE DEGRADERS OF HELIOS AND METHODS OF USE | Dana-Farber Cancer Institute, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022081976-A1 | PIPERIDINYL SMALL MOLECULE DEGRADERS OF HELIOS AND METHODS OF USE | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
| CN-109651363-B | Aminomethylated imidazo [1,2-a ] pyridine compound and preparation method thereof | 东华理工大学 | 2020-06-26 | — | — | CN | disclosed |
| US-20050260126-A1 | Diagnostic probes and remedies for diseases with accumulation of prion protein, and stains for prion protein | BF RESEARCH INSTITUTE (JP) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050260126-A1 | Diagnostic probes and remedies for diseases with accumulation of prion protein, and stains for prion protein | PRNP, PRPH, PCNP | ALDH1A3 785/4885ALDH1A1 1577/4885ALDH1A2 1056/4885 |
| US-20250283038-A1 | COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS | CXCL10, IL2, IFNG | ALDH1A3 3585/4885ALDH1A1 2221/4885ALDH1A2 3347/4885 |
| US-20240034723-A1 | PIPERIDINYL SMALL MOLECULE DEGRADERS OF HELIOS AND METHODS OF USE | IKZF2, IKZF1, NUTF2 | ALDH1A3 2094/4885ALDH1A1 2101/4885ALDH1A2 1684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.