Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6488312 | 0.92 | P2RX3 (0.42) | MRGPRX4P2RX3CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6488333 | 0.86 | MRGPRX4 (0.43) | MRGPRX4CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6502236 | 0.84 | MRGPRX4 (0.39) | MRGPRX4CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL7197594 | 0.81 | MRGPRX4 (0.39) | MRGPRX4CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6489573 | 0.81 | MAOB (0.39) | MRGPRX4CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6498704 | 0.80 | P2RX3 (0.45) | MRGPRX4P2RX3PTGER1 | |
| SCHEMBL6497968 | 0.79 | CYP1A2 (0.39) | CYP1A2CYP3A4CYP2D6CYP2C19GLA | |
| SCHEMBL6502677 | 0.78 | P2RX3 (0.40) | MRGPRX4P2RX3PTGER1 | |
| SCHEMBL7192439 | 0.78 | MRGPRX4 (0.40) | MRGPRX4CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6488927 | 0.78 | MRGPRX4 (0.44) | MRGPRX4CYP1A2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | MRGPRX4 2443/4885P2RX3 2660/4885CYP1A2 247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.