Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | F11 | P03951 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6488333 | 0.92 | MRGPRX4 (0.43) | CYP1A2CYP3A4CYP2C19CYP2D6KMT2A | |
| SCHEMBL6490408 | 0.85 | JMJD6 (0.41) | CYP1A2CYP3A4CYP2C19CYP2D6KMT2A | |
| SCHEMBL6487814 | 0.85 | MEN1 (0.43) | MAOBCYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL6498752 | 0.82 | MEN1 (0.41) | MAOBCYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL6490180 | 0.81 | LMNA (0.41) | CYP1A2CYP3A4CYP2C19CYP2D6KMT2A | |
| SCHEMBL6488312 | 0.81 | P2RX3 (0.42) | CYP1A2CYP3A4CYP2C19CYP2D6KMT2A | |
| SCHEMBL6491606 | 0.81 | MRGPRX4 (0.41) | CYP1A2CYP3A4CYP2C19CYP2D6KMT2A | |
| SCHEMBL7197594 | 0.81 | MRGPRX4 (0.39) | CYP1A2CYP3A4CYP2C19CYP2D6KMT2A | |
| SCHEMBL6489988 | 0.79 | DCTPP1 (0.40) | CYP1A2CYP3A4CYP2C19CYP2D6KMT2A | |
| SCHEMBL6497968 | 0.78 | CYP1A2 (0.39) | CYP1A2CYP3A4CYP2C19CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | MAOB 1631/4885CYP1A2 247/4885CYP3A4 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.