Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GALR2 | O43603 | 1/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
| ▸ | CCR6 | P51684 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474176 | 0.89 | LMNA (0.60) | LMNANPSR1ALDH1A1GALR2MITF | |
| SCHEMBL8954112 | 0.88 | SMN1; SMN2 (0.58) | LMNANPSR1ALDH1A1GALR2MITF | |
| SCHEMBL21989034 | 0.87 | SLC9A1 (0.52) | LMNANPSR1ALDH1A1GALR2MITF | |
| SCHEMBL3915677 | 0.86 | SLC9A1 (0.51) | LMNANPSR1ALDH1A1GALR2MITF | |
| SCHEMBL9899099 | 0.86 | MEN1 (0.47) | LMNAPOLBKMT2AMEN1KDM4E | |
| SCHEMBL30035016 | 0.86 | MEN1 (0.47) | LMNAPOLBKMT2AMEN1KDM4E | |
| SCHEMBL2128713 | 0.84 | SMN1; SMN2 (0.54) | LMNANPSR1ALDH1A1GALR2MITF | |
| SCHEMBL8767018 | 0.84 | LMNA (0.58) | LMNANPSR1ALDH1A1GALR2MITF | |
| SCHEMBL3915656 | 0.84 | SLC9A1 (0.56) | LMNANPSR1ALDH1A1GALR2MITF | |
| SCHEMBL8513944 | 0.84 | MAPT (0.55) | LMNANPSR1ALDH1A1GALR2MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6890934-B2 | Sulfonamide compounds and uses thereof as medicines | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-10 | — | — | US | disclosed |
| US-20030171396-A1 | Sulfonamide compounds and uses thereof as medicines | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2003-09-11 | — | — | US | disclosed |
| US-6573274-B1 | Treatment of the diseases curable based on a hypoglycemic action, and the diseases curable based on a cGMP-PDE inhibitory action, a smooth muscle relaxing action, a bronchodilating action, a vasodilating action, a smooth muscle | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2003-06-03 | — | — | US | disclosed |
| EP-1136492-A1 | SULFONAMIDE COMPOUNDS AND USES THEREOF AS MEDICINES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-09-26 | — | — | EP | disclosed |
| EP-0196910-B1 | Benzo[a]phenazine derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1991-01-02 | — | — | EP | disclosed |
| US-4686292-A | Benzo[α]phenazine antitumor agents | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1987-08-11 | — | — | US | disclosed |
| EP-0196910-A2 | Benzo[a]phenazine derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1986-10-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171396-A1 | Sulfonamide compounds and uses thereof as medicines | PDE2A, PDE3A, PDE5A | LMNA 2742/4885NPSR1 1412/4885ALDH1A1 476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.