Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | USP14 | P54578 | 1/20 | 0.34 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5844583 | 0.80 | KDM4E (0.40) | KDM4ETRPV4ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL10431359 | 0.78 | TSHR (0.53) | KDM4EGAATSHRMAPTALDH1A1 | |
| SCHEMBL29171081 | 0.77 | KDM4E (0.54) | KDM4EGAATSHRMAPTALDH1A1 | |
| SCHEMBL2661807 | 0.77 | KDM4E (0.54) | KDM4EMAPTALDH1A1NPSR1TDP1 | |
| SCHEMBL6503760 | 0.75 | AR (0.40) | TRPV4MAPTALDH1A1SLC34A1 | |
| SCHEMBL6506928 | 0.74 | TRPV4 (0.36) | KDM4EGAATRPV4ALDH1A1USP14 | |
| SCHEMBL23245429 | 0.73 | TRPV4 (0.44) | KDM4EGAATRPV4MAPTALDH1A1 | |
| SCHEMBL12877149 | 0.72 | TSHR (0.59) | KDM4EGAATSHRMAPTALDH1A1 | |
| SCHEMBL6729831 | 0.72 | EGLN2 (0.39) | KDM4ETRPV4ALDH1A1HTTUSP14 | |
| SCHEMBL6500898 | 0.72 | SLC34A1 (0.36) | KDM4EGAATRPV4MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2184675-A | — | — | None | — | — | JP | disclosed |
| US-6906006-B1 | N-arly-substituted nitrogen-containing heterocycles, processes and novel intermediates for their preparation, and their use as herbicides and plant growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 2005-06-14 | — | — | US | disclosed |
| US-5554580-A | N-aryl-substituted nitrogen-containing heterocycles intermediates and their use as herbicides and plant growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1996-09-10 | — | — | US | disclosed |
| EP-0370332-B1 | N-aryl-nitrogen heterocycles, process and intermediates for their production and their use as herbicides and in controlling the growth of plants | BAYER AG (DE) | 1994-03-30 | — | — | EP | disclosed |
| US-5006148-A | N-aryl-substituted nitrogen-containing heterocycles, and their use as herbicides and plant growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-09 | — | — | US | disclosed |
| EP-0382034-A1 | N-aryl-nitrogenated heterocycles | BAYER AG (DE) | 1990-08-16 | — | — | EP | disclosed |
| JP-H02184675-A | N-ARYL-SUBSTITUTED NITROGEN-CONTAINING HETEROCYCLE, PRODUCTION THEREOF, NOVEL INTERMEDIATE FOR THE HETEROCYCLE AND THEIR USE AS HERBICIDE AND PLANT GROWTH REGULATOR | BAYER AG | 1990-07-19 | — | — | JP | disclosed |
| EP-0370332-A1 | N-aryl-nitrogen heterocycles, process and intermediates for their production and their use as herbicides and in controlling the growth of plants | BAYER AG (DE) | 1990-05-30 | — | — | EP | disclosed |