Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | USP14 | P54578 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503891 | 0.84 | SLC34A1 (0.32) | SLC34A1S1PR1 | |
| SCHEMBL11664985 | 0.77 | LMNA (0.39) | SLC34A1TP53MAPT | |
| SCHEMBL10563884 | 0.76 | SLC34A1 (0.36) | SLC34A1 | |
| SCHEMBL10561933 | 0.75 | SLC34A1 (0.35) | SLC34A1 | |
| SCHEMBL7941448 | 0.75 | SLC34A1 (0.38) | SLC34A1ALDH1A1 | |
| SCHEMBL6503760 | 0.74 | AR (0.40) | SLC34A1TRPV4MAPTEGLN2ALDH1A1 | |
| SCHEMBL6494499 | 0.72 | KDM4E (0.59) | SLC34A1TRPV4GAAMAPTUSP14 | |
| SCHEMBL10564557 | 0.71 | PPOX (0.49) | GAAALDH1A1KDM4EPOLBS1PR1 | |
| SCHEMBL9820824 | 0.71 | ALDH1A1 (0.38) | SLC34A1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL10560134 | 0.70 | PPOX (0.37) | SLC34A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6906006-B1 | N-arly-substituted nitrogen-containing heterocycles, processes and novel intermediates for their preparation, and their use as herbicides and plant growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 2005-06-14 | — | — | US | disclosed |
| US-6395683-B1 | CHEMICAL INTERMEDIATE FOR HERBICIDES; APPLYING TO PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-05-28 | — | — | US | disclosed |
| EP-0757673-B1 | HETEROCYCLYLBENZONITRILES | BAYER AG (DE) | 2001-10-04 | — | — | EP | disclosed |
| US-6100420-A | 2-(SULFONYLAMINO OR DERIVATIVE THEREOF),4-AMINO,5-(HALO OR HYDROGEN)BENZONITRILE OF GIVEN FORMULA; CHEMICAL INTERMEDIATE TO CORRESPONDING 4-HETEROCYCLE BENZONITRILE HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-08-08 | — | — | US | disclosed |
| US-5858925-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-12 | — | — | US | disclosed |
| EP-0757673-A1 | HETEROCYCLYLBENZONITRILES | BAYER AG (DE) | 1997-02-12 | — | — | EP | disclosed |
| US-5554580-A | N-aryl-substituted nitrogen-containing heterocycles intermediates and their use as herbicides and plant growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1996-09-10 | — | — | US | disclosed |
| WO-1995029158-A1 | HETEROCYCLYLBENZONITRILES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-11-02 | — | — | WO | disclosed |
| EP-0370332-B1 | N-aryl-nitrogen heterocycles, process and intermediates for their production and their use as herbicides and in controlling the growth of plants | BAYER AG (DE) | 1994-03-30 | — | — | EP | disclosed |
| US-5006148-A | N-aryl-substituted nitrogen-containing heterocycles, and their use as herbicides and plant growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-09 | — | — | US | disclosed |
| EP-0370332-A1 | N-aryl-nitrogen heterocycles, process and intermediates for their production and their use as herbicides and in controlling the growth of plants | BAYER AG (DE) | 1990-05-30 | — | — | EP | disclosed |