Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.35 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.33 |
| ▸ | BCAT1 | P54687 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.32 |
| ▸ | USP14 | P54578 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5843626 | 0.80 | BCAT2 (0.36) | KDM4EBCAT2BCAT1 | |
| SCHEMBL6494499 | 0.80 | KDM4E (0.59) | KDM4ETRPV4CYP11B1CYP11B2USP14 | |
| SCHEMBL6506928 | 0.75 | TRPV4 (0.36) | KDM4ETRPV4BCAT2BCAT1AR | |
| SCHEMBL5844322 | 0.75 | CYP11B1 (0.39) | KDM4ETRPV4CYP11B1CYP11B2BCAT2 | |
| SCHEMBL6729831 | 0.73 | EGLN2 (0.39) | KDM4ETRPV4BCAT2BCAT1EGLN2 | |
| SCHEMBL8787649 | 0.72 | TRPV4 (0.33) | KDM4ETRPV4KHKUSP14CHRM2 | |
| SCHEMBL8786897 | 0.72 | TRPV4 (0.33) | KDM4ETRPV4USP14ALDH1A1 | |
| SCHEMBL9138271 | 0.72 | TRPV4 (0.33) | KDM4ETRPV4CYP11B1CYP11B2BCAT2 | |
| SCHEMBL6730393 | 0.72 | MEN1 (0.35) | KDM4ETRPV4CYP11B1CYP11B2EGLN2 | |
| SCHEMBL6730381 | 0.72 | GPR139 (0.36) | KDM4ECYP11B1CYP11B2EGLN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7012041-B2 | Phenylpyridazinones | BAYER AG (DE) | 2006-03-14 | — | — | US | disclosed |
| EP-0832072-B1 | PHENYLPYRIDAZINONES | BAYER CROPSCIENCE AG (DE) | 2003-09-24 | — | — | EP | disclosed |
| US-20030119673-A1 | Phenylpyridazinones | LINKER KARL-HEINZ (DE) | 2003-06-26 | — | — | US | disclosed |
| US-6551963-B1 | For controlling unwanted vegetation | BAYER AKTIENGESELLSCHAFT (DE) | 2003-04-22 | — | — | US | disclosed |
| EP-0832072-A1 | PHENYLPYRIDAZINONES | BAYER AG (DE) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996039392-A1 | PHENYLPYRIDAZINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119673-A1 | Phenylpyridazinones | CYP2D6, CYP1A1, CYP1B1 | KDM4E 1610/4885TRPV4 3210/4885CYP11B1 97/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.