Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6493957 | 0.82 | ADORA3 (0.55) | ALDH1A1HPGDADORA3MDM2SMN1; SMN2 | |
| SCHEMBL27633486 | 0.82 | ALDH1A1 (0.65) | ALDH1A1HPGDPTGS2PTGS1SMN1; SMN2 | |
| SCHEMBL5759689 | 0.82 | ALDH1A1 (0.69) | ALDH1A1HPGDPTGS2PTGS1MAPK1 | |
| SCHEMBL6258083 | 0.81 | ADORA3 (0.53) | ALDH1A1HPGDADORA3MDM2SMN1; SMN2 | |
| SCHEMBL6493940 | 0.80 | ADORA3 (0.52) | ALDH1A1HPGDADORA3MDM2SMN1; SMN2 | |
| SCHEMBL9456779 | 0.80 | ADORA3 (0.52) | ALDH1A1HPGDADORA3MDM2SMN1; SMN2 | |
| SCHEMBL6530759 | 0.78 | ALDH1A1 (0.51) | ALDH1A1HPGDADORA3MDM2SMN1; SMN2 | |
| SCHEMBL4754842 | 0.78 | CYP1A2 (0.49) | ALDH1A1HPGDSMN1; SMN2LMNAMAPT | |
| SCHEMBL20376677 | 0.76 | ALDH1A1 (0.50) | ALDH1A1HPGDPTGS2PTGS1SMN1; SMN2 | |
| SCHEMBL3120984 | 0.74 | MAPT (0.58) | ALDH1A1HPGDSMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014765-A1 | Aryl-heteroaromatic products, compositions comprising them and use | AVENTIS PHARMA S.A. (FR) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014765-A1 | Aryl-heteroaromatic products, compositions comprising them and use | AHR, ARNT, MYC | ALDH1A1 240/4885HPGD 664/4885ADORA3 987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.