Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 8/20 | 0.57 |
| ▸ | RAB9A | P51151 | 8/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 3/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27467205 | 0.88 | NR1H4 (0.63) | NR1H4NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL27832067 | 0.79 | NPC1 (0.55) | NR1H4NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL27001834 | 0.78 | NR1H4 (0.70) | NR1H4NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL29936603 | 0.77 | NPC1 (0.63) | NR1H4NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6490110 | 0.77 | RAB9A (0.70) | NR1H4NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL12581664 | 0.76 | GPR55 (0.63) | NR1H4NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL12101816 | 0.75 | CYP3A4 (0.74) | NPC1RAB9ASMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL6495190 | 0.74 | NR1H4 (0.52) | NR1H4NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6495191 | 0.74 | NR1H4 (0.52) | NR1H4NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL2888002 | 0.73 | HDAC4 (0.50) | ALDH1A1S1PR1CYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6893650-B1 | N2-phenylamidine derivatives | BAYER CROPSCIENCE GMBH (DE) | 2005-05-17 | — | — | US | disclosed |
| EP-1150944-B1 | N2-PHENYLAMIDINE DERIVATIVES | BAYER CROPSCIENCE GMBH (DE) | 2003-08-20 | — | — | EP | disclosed |
| EP-1150944-A1 | N2-PHENYLAMIDINE DERIVATIVES | Aventis CropScience GmbH (DE) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000046184-A1 | N2-PHENYLAMIDINE DERIVATIVES | AVENTIS CROPSCIENCE GMBH (FR) | 2000-08-10 | — | — | WO | disclosed |